Glioblastoma multiforme patient survival prediction

S Rajput, R Agravat, M Roy, MS Raval - Proceedings of 2021 International …, 2022 - Springer
S Rajput, R Agravat, M Roy, MS Raval
Proceedings of 2021 International Conference on Medical Imaging and Computer …, 2022Springer
Glioblastoma Multiforme is a very aggressive type of brain tumor. Due to spatial and
temporal intra-tissue inhomogeneity, location and the extent of the cancer tissue, it is difficult
to detect and dissect the tumor regions. In this paper, we propose survival prognosis models
using four regressors operating on handcrafted image-based and radiomics features. We
hypothesize that the radiomics shape features have the highest correlation with survival
prediction. The proposed approaches were assessed on the Brain Tumor Segmentation …
Abstract
Glioblastoma Multiforme is a very aggressive type of brain tumor. Due to spatial and temporal intra-tissue inhomogeneity, location and the extent of the cancer tissue, it is difficult to detect and dissect the tumor regions. In this paper, we propose survival prognosis models using four regressors operating on handcrafted image-based and radiomics features. We hypothesize that the radiomics shape features have the highest correlation with survival prediction. The proposed approaches were assessed on the Brain Tumor Segmentation (BraTS-2020) challenge dataset. The highest accuracy of image features with random forest regressor approach was 51.5% for the training and 51.7% for the validation dataset. The gradient boosting regressor with shape features gave an accuracy of 91.5% and 62.1% on training and validation datasets respectively. It is better than the BraTS 2020 survival prediction challenge winners on the training and validation datasets. Our work shows that handcrafted features exhibit a strong correlation with survival prediction. The consensus based regressor with gradient boosting and radiomics shape features is the best combination for survival prediction.
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