Reactive oxygen species (ROS)-responsive nanoprobe for bioimaging and targeting therapy of osteoarthritis

C Shen, M Gao, H Chen, Y Zhan, Q Lan, Z Li… - Journal of …, 2021 - Springer
Stimulus-responsive therapy that allows precise imaging-guided therapy is limited for
osteoarthritis (OA) therapy due to the selection of proper physiological markers as stimulus. Based …

Nrf2-regulated miR-380-3p blocks the translation of Sp3 protein and its mediation of paraquat-induced toxicity in mouse neuroblastoma N2a cells

Z Cai, F Zheng, Y Ding, Y Zhan, R Gong… - Toxicological …, 2019 - academic.oup.com
Laboratorial and epidemiological research has established a relationship between paraquat
(PQ) exposure and a risk for Parkinson’s disease. Previously, we have investigated the …

Cartilage-targeting poly (ethylene glycol)(PEG)-formononetin (FMN) nanodrug for the treatment of osteoarthritis

…, Q Lan, X Liang, J Zhao, H Huang, Y Zhan… - Journal of …, 2021 - Springer
Intra-articular (IA) injection is an efficient treatment for osteoarthritis, which will minimize
systemic side effects. However, the joint experiences rapid clearance of therapeutics after intra-…

Paraquat and MPTP alter microRNA expression profiles, and downregulated expression of miR‐17‐5p contributes to PQ‐induced dopaminergic neurodegeneration

Q Wang, Y Zhan, N Ren, Z Wang… - Journal of Applied …, 2018 - Wiley Online Library
… Qingqing Wang and Yanting Zhan, these two authors contributed equally to this work.…
Qingqing Wang and Yanting Zhan, these two authors contributed equally to this work.Search for …

Enhanced spectral–spatial residual attention network for hyperspectral image classification

Y Zhan, K Wu, Y Dong - IEEE Journal of Selected Topics in …, 2022 - ieeexplore.ieee.org
Deep learning has achieved good performance in hyperspectral image classification (HSIC).
Many methods based on deep learning use deep and complex network structures to extract …

Multiscale Feature Search-Based Graph Convolutional Network for Hyperspectral Image Classification

K Wu, Y Zhan, Y An, S Li - Remote Sensing, 2024 - mdpi.com
With the development of hyperspectral sensors, the availability of hyperspectral images (HSIs)
has increased significantly, prompting advancements in deep learning-based …

Reactive oxygen species regulate miR‐17‐5p expression via DNA methylation in paraquat‐induced nerve cell damage

Y Zhan, Z Guo, F Zheng, Z Zhang, K Li… - Environmental …, 2020 - Wiley Online Library
There is emerging evidence suggesting that oxidative stress and DNA methylation can alter
miRNA expression. However, little is known on the mechanism of miR‐17‐5p expression …

Role of histone acetylation in activation of nuclear factor erythroid 2-related factor 2/heme oxygenase 1 pathway by manganese chloride

Z Zhang, Z Guo, Y Zhan, H Li, S Wu - Toxicology and Applied …, 2017 - Elsevier
Manganese neurotoxicity is characterized by Parkinson-like symptoms with degeneration of
dopaminergic neurons in the basal ganglia as the principal pathological feature. …

A Siamese network based on multiple attention and multilayer transformers for change detection

W Tang, K Wu, Y Zhang, Y Zhan - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Deep learning (DL) networks have demonstrated promising performance in high-resolution
remote sensing (RS) image change detection (CD). The transformer can enhance the …

Cannabidiol‐Loaded Poly Lactic‐Co‐Glycolic Acid Nanoparticles with Improved Bioavailability as a Potential for Osteoarthritis Therapeutic

Z Jin, Y Zhan, L Zheng, Q Wei, S Xu, Z Qin - Chembiochem, 2023 - Wiley Online Library
Cannabidiol (CBD) is a non‐intoxicating cannabinoid from cannabis sativa that has
demonstrated efficacious against inflammation, which can be considered as a potential drug for …