User profiles for Thorsten Krause

Thorsten Krause

German Research Center for Artificial Intelligence
Verified email at dfki.de
Cited by 20

Meperidine Exerts Agonist Activity at the α2B-Adrenoceptor Subtype

…, MF Davies, PH Tonner, TKW Krause… - The Journal of the …, 2002 - pubs.asahq.org
Background The opioid agonist meperidine has actions, such as antishivering, that are more
pronounced than those of other opioid agonists and that are not blocked with nonselective …

Cell penetrating peptides: a comparative transport analysis for 474 sequence motifs

K Ramaker, M Henkel, T Krause, N Röckendorf… - Drug Delivery, 2018 - Taylor & Francis
Delivering reagents into cells is a key demand in molecular medicine. The vehicle of choice
is often cell penetrating peptides (CPPs), which can ferry conjugated cargo across …

[HTML][HTML] The gut wall provides an effective barrier against nanoparticle uptake

H Sinnecker, T Krause, S Koelling… - Beilstein journal of …, 2014 - beilstein-journals.org
Background: The omnipresence of nanoparticles (NPs) in numerous goods has led to a
constant risk of exposure and inadvertent uptake for humans. This situation calls for thorough …

Enabling Individualized and Adaptive Learning–The Value of an AI-Based Recommender System for Users of Adult and Continuing Education Platforms

S Digel, T Krause, C Biel - International Conference on Artificial …, 2023 - Springer
The extent to which individualized and adaptive learning can be supported by recommender
systems is increasingly being discussed in the field of adult and continuing education (ACE)…

IgE epitope profiling for allergy diagnosis and therapy–parallel analysis of a multitude of potential linear epitopes using a high throughput screening platform

T Krause, N Röckendorf, B Meckelein… - Frontiers in …, 2020 - frontiersin.org
Immunoglobulin E (IgE) is pivotal for manifestation and persistence of most immediate-type
allergies and some asthma phenotypes. Consequently, IgE represents a crucial target for …

Reduced O6-Methylguanine Repair in Fibroblast Cultures from Patients with Lung Cancer

HW Rüdiger, U Schwartz, E Serrand, M Stief, T Krause… - Cancer Research, 1989 - AACR
The activity of O 6 -methylguanine-DNA methyltransferase was determined in fibroblast cultures
from 45 patients with lung cancer, 39 patients with cutaneous malignant melanoma, and …

Propofol anesthesia in children does not induce sister chromatid exchanges in lymphocytes

TKW Krause, L Jansen, J Scholz, H Böttcher… - … /Genetic Toxicology and …, 2003 - Elsevier
Background: Propofol is frequently used for general anesthesia in children although little is
known about possible genotoxic effects in humans. We investigated the formation of sister …

Hydroxyethyl starch (HES 130/0.4) impairs intestinal barrier integrity and metabolic function: findings from a mouse model of the isolated perfused small intestine

…, H Dombrowsky, K Zitta, B Bein, T Krause… - PloS one, 2015 - journals.plos.org
Background The application of hydroxyethyl starch (HES) for volume resuscitation is
controversially discussed and clinical studies have suggested adverse effects of HES substitution, …

Mitigating Exposure Bias in Recommender Systems–A Comparative Analysis of Discrete Choice Models

T Krause, A Deriyeva, JH Beinke, GY Bartels… - ACM Transactions on …, 2024 - dl.acm.org
When implicit feedback recommender systems expose users to items, they influence the
users’ choices and, consequently, their own future recommendations. This effect is known as …

Breeding cell penetrating peptides: optimization of cellular uptake by a function-driven evolutionary process

T Krause, N Röckendorf, N El-Sourani… - Bioconjugate …, 2018 - ACS Publications
In nature, building block-based biopolymers can adapt to functional and environmental
demands by recombination and mutation of the monomer sequence. We present here an …