Functional anatomy and hemodynamic characteristics of vasa vasorum in the walls of porcine coronary arteries

…, NM Malyar, LA Fitzpatrick, PE Beighley… - … Record Part A …, 2003 - Wiley Online Library
In this study vasa vasorum in the walls of porcine coronary arteries were examined, using
three‐dimensional (3D) micro‐CT scanning techniques. These techniques leave the 3D …

Correlation of Vasa Vasorum Neovascularization and Plaque Progression in Aortas of Apolipoprotein E−/−/Low-Density Lipoprotein−/− Double Knockout Mice

…, DG Sedding, G Walker, PE Beighley… - … , and vascular biology, 2006 - Am Heart Assoc
Objective— We hypothesized that apolipoprotein E (apoE) −/− /low-density lipoprotein (LDL)
−/− double knockout mice might develop vasa vasorum (VV) in association with advanced …

Impact of coronary vasa vasorum functional structure on coronary vessel wall perfusion distribution

…, NM Malyar, M Rosol, PE Beighley… - American Journal …, 2003 - journals.physiology.org
Noncoronary vasa vasorum have been described as networks of microvessels in the wall of
arteries and veins. However, we have shown, using microcomputerized tomography (micro-…

Automatic segmentation of 3D micro-CT coronary vascular images

J Lee, P Beighley, E Ritman, N Smith - Medical image analysis, 2007 - Elsevier
Although there are many algorithms available in the literature aimed at segmentation and
model reconstruction of 3D angiographic images, many are focused on characterizing only a …

Relationship between arterial diameter and perfused tissue volume in myocardial microcirculation: a micro-CT-based analysis

NM Malyar, M Gössl, PE Beighley… - American Journal of …, 2004 - journals.physiology.org
The volume of myocardial tissue that is perfused by an epicardial coronary artery has been
shown to be predictably related to the diameter of the epicardial arterial lumen. However, to …

3D architecture of myocardial microcirculation in intact rat heart: a study with micro-CT

PE Beighley, PJ Thomas, SM Jorgensen… - Analytical and …, 1997 - Springer
The branching geometry of the coronary arterial tree may play a significant role in the observed
spatial heterogeneity in myocardial perfusion. To provide more insight into this possibility …

Synchrotron-based micro-CT of in-situ biological basic functional units and their integration

EL Ritman, SM Jorgensen, PE Beighley… - Developments in X …, 1997 - spiedigitallibrary.org
Use of synchrotron generated x-ray for micro-CT is particularly powerful for several reasons.
These include the high x-ray flux which permits short duration exposure and hence scan …

Intramyocardial blood volume, perfusion and transit time in response to embolization of different sized microvessels

S Möhlenkamp, PE Beighley, EA Pfeifer… - Cardiovascular …, 2003 - academic.oup.com
Objective: To study the role of the coronary microcirculation in response to different-sized
microemboli, we measured changes in intramyocardial microvascular blood volume (Bv), …

Microvascular development in porcine right and left ventricular walls

H Ohuchi, PE Beighley, Y Dong, M Zamir… - Pediatric research, 2007 - nature.com
Patients with congenital heart disease who have a morphological right ventricle (RV) serving
as a systemic ventricle have an increased incidence of RV dysfunction. A different structural …

Relation of nonperfused myocardial volume and surface area to left ventricular performance in coronary microembolization

NM Malyar, LO Lerman, M Gössl, PE Beighley… - Circulation, 2004 - Am Heart Assoc
Background— After occlusion of an epicardial artery, left ventricular (LV) dysfunction is
closely related to the volume of nonperfused myocardium (NPM). The impact of coronary …