User profiles for Loubna Akhabir
 | Loubna AkhabirVerified email at alumni.ubc.ca Cited by 1378 |
Surrogate adiposity markers and mortality
Importance Body mass index (BMI) is an easily obtained adiposity surrogate. However, there
is variability in body composition and adipose tissue distribution between individuals with …
is variability in body composition and adipose tissue distribution between individuals with …
Genome‐wide association studies for discovery of genes involved in asthma
L Akhabir, AJ Sandford - Respirology, 2011 - Wiley Online Library
Asthma is the result of a complex interaction between environmental factors and genetic
variants that confer susceptibility. Studies of the genetics of asthma have previously been …
variants that confer susceptibility. Studies of the genetics of asthma have previously been …
Associations of IL6 polymorphisms with lung function decline and COPD
Background: Interleukin-6 (IL6) is a pleiotropic pro-inflammatory and immunomodulatory
cytokine which probably plays an important role in the pathogenesis of chronic obstructive …
cytokine which probably plays an important role in the pathogenesis of chronic obstructive …
GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia
10. Hatter Institute for Cardiovascular Diseases Research in Africa (HICRA) & Cape Heart
Institute (CHI), Department of Medicine, University of Cape Town, South Africa
Institute (CHI), Department of Medicine, University of Cape Town, South Africa
Analyses of associations with asthma in four asthma population samples from Canada and Australia
Asthma, atopy, and related phenotypes are heterogeneous complex traits, with both genetic
and environmental risk factors. Extensive research has been conducted and over hundred …
and environmental risk factors. Extensive research has been conducted and over hundred …
Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis, and bronchopulmonary dysplasia
…, CD Fjell, J Yan, L Akhabir… - The Journal of …, 2013 - journals.aai.org
Respiratory diseases are the most frequent chronic illnesses in babies and children.
Although a vigorous innate immune system is critical for maintaining lung health, a balanced …
Although a vigorous innate immune system is critical for maintaining lung health, a balanced …
[HTML][HTML] Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic …
Background Peanut allergy (PA) is a complex disease with both environmental and genetic
risk factors. Previously, PA loci were identified in filaggrin (FLG) and HLA in candidate gene …
risk factors. Previously, PA loci were identified in filaggrin (FLG) and HLA in candidate gene …
Genetics of interleukin 1 receptor-like 1 in immune and inflammatory diseases
L Akhabir, A Sandford - Current genomics, 2010 - benthamdirect.com
Interleukin 1 receptor-like 1 (IL1RL1) is gaining in recognition due to its involvement in
immune/inflammatory disorders. Well-designed animal studies have shown its critical role in …
immune/inflammatory disorders. Well-designed animal studies have shown its critical role in …
Associations and interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related …
BACKGROUND: The innate immune system is essential for host survival because of its
ability to recognize invading pathogens and mount defensive responses. OBJECTIVES: We …
ability to recognize invading pathogens and mount defensive responses. OBJECTIVES: We …
A thymic stromal lymphopoietin polymorphism may provide protection from asthma by altering gene expression
…, DD Sommer, JA Denburg, L Akhabir - Clinical & …, 2020 - Wiley Online Library
Background Genome‐wide association studies have identified associations of the single
nucleotide polymorphism rs1837253 in the thymic stromal lymphopoietin (TSLP) gene with …
nucleotide polymorphism rs1837253 in the thymic stromal lymphopoietin (TSLP) gene with …