Ion exchange membranes (IEMs) have great potential in diverse applications and play
prominent roles in addressing energy and environment related issues. Over the past decade, the …

Proton-conducting mixed matrix membranes (PC-MMMs) have received considerable
interest as promising materials that combine the properties of, and create synergism from …

How neuronal activity changes cerebral blood flow is of biological and practical importance.
The rodent whisker-barrel system has special merits as a model for studies of changes in …

Niemann-Pick C1-like 1 (NPC1L1) is a polytopic transmembrane protein that plays a critical
role in cholesterol absorption. Ezetimibe, a hypocholesterolemic drug, has been reported to …

Many cytosolic proteins lacking a signal peptide, called leaderless cargoes, are secreted
through unconventional secretion. Vesicle trafficking is a major pathway involved. It is unclear …

The sharp-interface CURVIB approach of Ge and Sotiropoulos [L. Ge, F. Sotiropoulos, A
numerical method for solving the 3D unsteady incompressible Navier–Stokes equations in …

Membranes of sub‐2‐nanometer channels show high ion transport rates, but it remains a
great challenge to design such membranes with desirable ion selectivities for ion separation …

10.7554/eLife.00947.001 Autophagy is a catabolic process for bulk degradation of cytosolic
materials mediated by double-membraned autophagosomes. The membrane determinant to …

A novel numerical method is developed that integrates boundary-conforming grids with a
sharp interface, immersed boundary methodology. The method is intended for simulating …

10.7554/eLife.11205.001 Recent evidence suggests that autophagy facilitates the
unconventional secretion of the pro-inflammatory cytokine interleukin 1β (IL-1β). Here, we …