Vacuolization of hematopoietic precursors: an enigma with multiple etiologies

…, S Pagliuca, L Durkin, L Terkawi… - Blood, The Journal …, 2021 - ashpublications.org
Cytoplasmic vacuoles in precursors can be seen in a number of clinical settings, including
copper deficiency, zinc toxicity, alcohol abuse, antibiotic treatment, myelodysplasia, and …

Molecular landscape of immune pressure and escape in aplastic anemia

…, S Hergalant, N Nadarajah, A Wahida, L Terkawi… - Leukemia, 2023 - nature.com
Idiopathic aplastic anemia (IAA) pathophysiology is dominated by autoreactivity of human
leukocyte antigen (HLA)-restricted T-cells against antigens presented by hematopoietic stem …

The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders

…, S Kongkiatkamon, L Terkawi… - Blood, The Journal …, 2021 - ashpublications.org
Idiopathic aplastic anemia (IAA) is a rare autoimmune bone marrow failure (BMF) disorder
initiated by a human leukocyte antigen (HLA)-restricted T-cell response to unknown antigens. …

Molecular patterns identify distinct subclasses of myeloid neoplasia

…, A Durmaz, W Bahaj, C Gurnari, L Terkawi… - Nature …, 2023 - nature.com
Genomic mutations drive the pathogenesis of myelodysplastic syndromes and acute myeloid
leukemia. While morphological and clinical features have dominated the classical criteria …

Clinical and basic implications of dynamic T cell receptor clonotyping in hematopoietic cell transplantation

…, S Hong, R Zhao, S Kongkiatkamon, L Terkawi… - JCI …, 2021 - pmc.ncbi.nlm.nih.gov
TCR repertoire diversification constitutes a foundation for successful immune reconstitution
after allogeneic hematopoietic cell transplantation (allo-HCT). Deep TCR Vβ sequencing of …

Implication of PIGA genotype on erythrocytes phenotype in Paroxysmal Nocturnal Hemoglobinuria

…, BJ Patel, H Awada, S Kongkiatkamon, L Terkawi… - Leukemia, 2021 - nature.com
Somatic mutations of the X-linked phosphatidylinositol N-acetylglucosaminyltransferase
subunit A (PIGA) gene in hematopoietic stem cells are the key molecular events in the …

Molecular and clinical analyses of PHF6 mutant myeloid neoplasia provide their pathogenesis and therapeutic targeting

Y Kubota, X Gu, L Terkawi, J Bodo… - Nature …, 2024 - nature.com
PHF6 mutations (PHF6 MT ) are identified in various myeloid neoplasms (MN). However,
little is known about the precise function and consequences of PHF6 in MN. Here we show …

Rare germline alterations of myeloperoxidase predispose to myeloid neoplasms

S Kongkiatkamon, L Terkawi, Y Guan, V Adema… - Leukemia, 2022 - nature.com
Myeloperoxidase (MPO) gene alterations with variable clinical penetrance have been found
in hereditary MPO deficiency, but their leukemia association in patients and carriers has not …

Phase change memory faults

MG Mohammad, L Terkawi… - … Conference on VLSI …, 2006 - ieeexplore.ieee.org
Chalcogenide based phase change memory (PCM) is a promising type of non-volatile memory
that possibly replace the currently wide spread flash memory. Current research on PCMs …

Fault collapsing for flash memory disturb faults

MG Mohammad, L Terkawi - European Test Symposium (ETS' …, 2005 - ieeexplore.ieee.org
Disturb failures are considered the most predominant failure mode in flash memories. Disturb
faults are highly dependant on the core memory cell structure, manufacturing technology, …