User profiles for Joshua D. Kangas
 | Joshua D. KangasAssistant Teaching Professor, Carnegie Mellon University Verified email at andrew.cmu.edu Cited by 631 |
Active machine learning-driven experimentation to determine compound effects on protein patterns
10.7554/eLife.10047.001 High throughput screening determines the effects of many conditions
on a given biological target. Currently, to estimate the effects of those conditions on other …
on a given biological target. Currently, to estimate the effects of those conditions on other …
Determining the subcellular location of new proteins from microscope images using local features
Motivation: Evaluation of previous systems for automated determination of subcellular
location from microscope images has been done using datasets in which each location class …
location from microscope images has been done using datasets in which each location class …
Efficient discovery of responses of proteins to compounds using active learning
Background Drug discovery and development has been aided by high throughput screening
methods that detect compound effects on a single target. However, when using focused …
methods that detect compound effects on a single target. However, when using focused …
Efficient modeling and active learning discovery of biological responses
High throughput and high content screening involve determination of the effect of many
compounds on a given target. As currently practiced, screening for each new target typically …
compounds on a given target. As currently practiced, screening for each new target typically …
10 simple rules for teaching wet-lab experimentation to computational biology students, ie, turning computer mice into lab rats
Graduate students in computational biology have strong quantitative backgrounds but are
often quite limited in their understanding of the theory, approach, and practice of biological …
often quite limited in their understanding of the theory, approach, and practice of biological …
A method for characterizing phenotypic changes in highly variable cell populations and its application to high content screening of Arabidopsis thaliana protoplasts
GR Johnson, JD Kangas, A Dovzhenko… - Cytometry Part …, 2017 - Wiley Online Library
Quantitative image analysis procedures are necessary for the automated discovery of effects
of drug treatment in large collections of fluorescent micrographs. When compared to their …
of drug treatment in large collections of fluorescent micrographs. When compared to their …
Titrating‐delay matching‐to‐sample in the pigeon
… Correspondence concerning this article can be directed to Brian D. Kangas, at the
Department of Psychology, University of Florida, PO Box 112250, Gainesville, FL 32611 (e-mail: […
Department of Psychology, University of Florida, PO Box 112250, Gainesville, FL 32611 (e-mail: […
An Assessment of Frontal Lobe Activity and BDNF Levels Following Concussion in Collegiate Athletes: A Near-Infrared Spectroscopy Study
KJ Kangas - 2017 - search.proquest.com
… Joshua Carlson. The first aim of the larger study is to assess the extent to which NIRS can
be used to assess frontal lobe activity in patients with concussion. A range of concussive …
be used to assess frontal lobe activity in patients with concussion. A range of concussive …
[BOOK][B] Active Learning for Drug Discovery
The use of high throughput screening methods has aided the drug discovery process allowing
for the testing of numerous compounds for effects on a single target protein. However, by …
for the testing of numerous compounds for effects on a single target protein. However, by …
Patient-centric Discovery by Active Learning (PeDAL) platform to predict drug response in a heterogeneous patient population
RJ Montgomery, AW Gilkey, JD Kangas… - Cancer …, 2023 - aacrjournals.org
Even after thorough preclinical testing, only 5% of oncology drug candidates entering clinical
trials ultimately get approved for use in patients. To find one drug that will be effective in the …
trials ultimately get approved for use in patients. To find one drug that will be effective in the …