Collapsin response mediator protein-2 (DPYSL2 or CRMP2) is a multifunctional adaptor
protein within the central nervous system. In the developing brain or cell cultures, CRMP2 …

Carboxypeptidase E (CPE) or carboxypeptidase H was first discovered in 1982 as an
enkephalin-convertase that cleaved a C-terminal basic residue from enkephalin precursors to …

Loss-of-function variants of TREM2 are associated with increased risk of Alzheimer’s disease
(AD), suggesting that activation of this innate immune receptor may be a useful therapeutic …

The release of intercellular messengers from synaptic (SVs) and dense-core vesicles (DCVs)
constitutes the primary mechanism for communication between neighboring or distant cells …

One of the main barriers to the enzymatic hydrolysis of cellulose results from its highly crystalline
structure. Pretreating biomass with ionic liquids (IL) increases enzyme accessibility and …

Background Binary diagnosis of coronary artery disease does not preserve the complexity of
disease or quantify its severity or its associated risk with death; hence, a quantitative marker …

Targeting glutamine metabolism via pharmacological inhibition of glutaminase has been
translated into clinical trials as a novel cancer therapy, but available drugs lack optimal safety …

Triggering receptor expressed on myeloid cells 2 ( TREM 2) is essential for the transition of
homeostatic microglia to a disease‐associated microglial state. To enhance TREM 2 activity, …

Bioengineering approaches that combine living cellular components with three-dimensional
scaffolds to generate motion can be used to develop a new generation of miniature robots. …

Development of cellulosic biofuels from non-food crops is currently an area of intense
research interest. Tailoring depolymerizing enzymes to particular feedstocks and pretreatment …