User profiles for Jingyi Qian

Jingyi Qian

Harvard Medical School, Brigham and Women's Hospital
Verified email at bwh.harvard.edu
Cited by 2750

Genetics of circadian rhythms and sleep in human health and disease

JM Lane, J Qian, E Mignot, S Redline… - Nature Reviews …, 2023 - nature.com
Circadian rhythms and sleep are fundamental biological processes integral to human health.
Their disruption is associated with detrimental physiological consequences, including …

Circadian system and glucose metabolism: implications for physiology and disease

J Qian, FAJL Scheer - Trends in Endocrinology & Metabolism, 2016 - cell.com
The circadian system serves one of the most fundamental properties present in nearly all
organisms: it generates 24-h rhythms in behavioral and physiological processes and enables …

Disruption of circadian rhythms accelerates development of diabetes through pancreatic beta-cell loss and dysfunction

JE Gale, HI Cox, J Qian, GD Block… - Journal of biological …, 2011 - journals.sagepub.com
Type 2 diabetes mellitus (T2DM) is complex metabolic disease that arises as a consequence
of interactions between genetic predisposition and environmental triggers. One recently …

[HTML][HTML] Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity

N Vujović, MJ Piron, J Qian, SL Chellappa… - Cell metabolism, 2022 - cell.com
Late eating has been linked to obesity risk. It is unclear whether this is caused by changes
in hunger and appetite, energy expenditure, or both, and whether molecular pathways in …

Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes

IC Mason, J Qian, GK Adler, FAJL Scheer - Diabetologia, 2020 - Springer
The circadian system generates endogenous rhythms of approximately 24 h, the
synchronisation of which are vital for healthy bodily function. The timing of many physiological …

High‐efficiency transmissive programmable metasurface for multimode OAM generation

X Bai, F Kong, Y Sun, G Wang, J Qian… - Advanced Optical …, 2020 - Wiley Online Library
Metasurfaces have been extensively studied for generating electromagnetic waves carrying
orbital angular momentum (OAM). In particular, programmable metasurfaces enable real‐…

Sex differences in the circadian misalignment effects on energy regulation

J Qian, CJ Morris, R Caputo, W Wang… - Proceedings of the …, 2019 - National Acad Sciences
Shift work causes circadian misalignment and is a risk factor for obesity. While some
characteristics of the human circadian system and energy metabolism differ between males and …

Melatonin effects on glucose metabolism: time to unlock the controversy

M Garaulet, J Qian, JC Florez, J Arendt… - Trends in Endocrinology …, 2020 - cell.com
The past decade has witnessed a revival of interest in the hormone melatonin, partly attributable
to the discovery that genetic variation in MTNR1B – the melatonin receptor gene – is a …

Consequences of exposure to light at night on the pancreatic islet circadian clock and function in rats

J Qian, GD Block, CS Colwell, AV Matveyenko - Diabetes, 2013 - Am Diabetes Assoc
There is a correlation between circadian disruption, type 2 diabetes mellitus (T2DM), and
islet failure. However, the mechanisms underlying this association are largely unknown. …

[HTML][HTML] Late eating is associated with cardiometabolic risk traits, obesogenic behaviors, and impaired weight loss

HS Dashti, P Gómez-Abellán, J Qian, A Esteban… - The American journal of …, 2021 - Elsevier
Background There is a paucity of evidence regarding the role of food timing on cardiometabolic
health and weight loss in adults. Objectives To determine whether late eating is cross-…