Assisted reproductive technologies do not enhance the variability of DNA methylation imprints in human
S Tierling, NY Souren, J Gries, C LoPorto… - Journal of medical …, 2010 - jmg.bmj.com
Background Assisted reproductive technologies (ART) such as in vitro fertilisation (IVF) and
intracytoplasmic sperm injection (ICSI) are believed to destabilise genomic imprints. An …
intracytoplasmic sperm injection (ICSI) are believed to destabilise genomic imprints. An …
Bi-PROF: bisulfite profiling of target regions using 454 GS FLX Titanium technology
The use of next generation sequencing has expanded our view on whole mammalian
methylome patterns. In particular, it provides a genome-wide insight of local DNA methylation …
methylome patterns. In particular, it provides a genome-wide insight of local DNA methylation …
Adult monozygotic twins discordant for intra-uterine growth have indistinguishable genome-wide DNA methylation profiles
NYP Souren, P Lutsik, G Gasparoni, S Tierling, J Gries… - Genome biology, 2013 - Springer
Background Low birth weight is associated with an increased adult metabolic disease risk. It
is widely discussed that poor intra-uterine conditions could induce long-lasting epigenetic …
is widely discussed that poor intra-uterine conditions could induce long-lasting epigenetic …
Identification and analysis of methylation call differences between bisulfite microarray and bisulfite sequencing data with statistical learning techniques
Background DNA methylation is an epigenetic modification known to play a prime role in
gene silencing and is an important topic in epigenetic research. However, due to technology-…
gene silencing and is an important topic in epigenetic research. However, due to technology-…
[PDF][PDF] Assisted reproductive technologies do not
S Tierling, NY Souren, J Gries - 2009 - researchgate.net
BACKGROUND: Assisted reproductive technologies (ART) such as in vitro fertilization (IVF)
and intracytoplasmic sperm injection (ICSI) are believed to destabilize genomic imprints. An …
and intracytoplasmic sperm injection (ICSI) are believed to destabilize genomic imprints. An …
DNA methylation studies on imprinted loci in a male monozygotic twin pair discordant for Beckwith–Wiedemann syndrome
S Tierling, NY Souren, S Reither, KD Zang… - Clinical …, 2011 - Wiley Online Library
Tierling S, Souren NY, Reither S, Zang KD, Meng‐Hentschel J, Leitner D, Oehl‐Jaschkowitz
B, Walter J. DNA methylation studies on imprinted loci in a male monozygotic twin pair …
B, Walter J. DNA methylation studies on imprinted loci in a male monozygotic twin pair …
Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells
The use of two kinase inhibitors (2i) enables derivation of mouse embryonic stem cells (ESCs)
in the pluripotent ground state. Using whole-genome bisulfite sequencing (WGBS), we …
in the pluripotent ground state. Using whole-genome bisulfite sequencing (WGBS), we …
Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo
Background DNA methylomes are extensively reprogrammed during mouse pre-implantation
and early germ cell development. The main feature of this reprogramming is a genome-…
and early germ cell development. The main feature of this reprogramming is a genome-…
In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases
… We thank Jasmin Gries for performing the 454 sequencing, Mathias Bader for programming
the scripts for the analysis of Hairpin-bisulfite data, and Pascal Giehr and Valentina Perrera …
the scripts for the analysis of Hairpin-bisulfite data, and Pascal Giehr and Valentina Perrera …
DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous
system with a modest concordance rate in monozygotic twins, which strongly argues for …
system with a modest concordance rate in monozygotic twins, which strongly argues for …