User profiles for Jacob Holm

Jacob Bak Holm, PhD - Verified email at bak-holm.com - Cited by 4799
Jacob Holm - Verified email at di.ku.dk - Cited by 1460
Jacob Rubæk Holm - Verified email at business.aau.dk - Cited by 1105

Human gut microbes impact host serum metabolome and insulin sensitivity

…, S Sunagawa, S Vieira-Silva, T Jørgensen, JB Holm… - Nature, 2016 - nature.com
Insulin resistance is a forerunner state of ischaemic cardiovascular disease and type 2
diabetes. Here we show how the human gut microbiome impacts the serum metabolome and …

Poly-logarithmic deterministic fully-dynamic algorithms for connectivity, minimum spanning tree, 2-edge, and biconnectivity

J Holm, K De Lichtenberg, M Thorup - Journal of the ACM (JACM), 2001 - dl.acm.org
Deterministic fully dynamic graph algorithms are presented for connectivity, minimum spanning
tree, 2-edge connectivity, and biconnectivity. Assuming that we start with no edges in a …

[HTML][HTML] Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism

…, A Balogh, S Kempa, P Träger, MM Zaiss, JB Holm… - Cell, 2020 - cell.com
Short-chain fatty acids are processed from indigestible dietary fibers by gut bacteria and
have immunomodulatory properties. Here, we investigate propionic acid (PA) in multiple …

Firm age and performance

A Coad, JR Holm, J Krafft, F Quatraro - Journal of Evolutionary Economics, 2018 - Springer
Amid increasing interest in firm age and its effects on firm performance, this special issue
offers an exhaustive review of the literature and a novel collection of evidence on the effects of …

Chronic Trichuris muris Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli

JB Holm, D Sorobetea, P Kiilerich, Y Ramayo-Caldas… - PloS one, 2015 - journals.plos.org
The intestinal microbiota is vital for shaping the local intestinal environment as well as host
immunity and metabolism. At the same time, epidemiological and experimental evidence …

Prevotella-to-Bacteroides ratio predicts body weight and fat loss success on 24-week diets varying in macronutrient composition and dietary fiber: results from a post …

…, LQ Bendtsen, JK Lorenzen, JB Holm… - International Journal of …, 2019 - nature.com
Background/objectives Individuals with high pre-treatment bacterial Prevotella-to-Bacteroides
(P/B) ratio have been reported to lose more body weight on diets high in fiber than …

Regional employment growth, shocks and regional industrial resilience: a quantitative analysis of the Danish ICT sector

JR Holm, CR Østergaard - Regional Studies, 2015 - Taylor & Francis
Holm JR and Østergaard CR Regional employment growth, shocks and regional industrial
resilience: a quantitative analysis of the Danish ICT sector, Regional Studies. The resilience …

Maintaining information in fully dynamic trees with top trees

S Alstrup, J Holm, KD Lichtenberg… - Acm Transactions on …, 2005 - dl.acm.org
We design top trees as a new simpler interface for data structures maintaining information in
a fully dynamic forest. We demonstrate how easy and versatile they are to use on a host of …

IRF8 transcription-factor-dependent classical dendritic cells are essential for intestinal T cell homeostasis

…, A Rivollier, M Demiri, KM Sitnik, L Pool, JB Holm… - Immunity, 2016 - cell.com
The role of dendritic cells (DCs) in intestinal immune homeostasis remains incompletely
defined. Here we show that mice lacking IRF8 transcription-factor-dependent DCs had reduced …

Streptococcus Species Abundance in the Gut Is Linked to Subclinical Coronary Atherosclerosis in 8973 Participants From the SCAPIS Cohort

…, G Varotsis, S Pita, N Nielsen, AC Eklund, JB Holm… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Gut microbiota have been implicated in atherosclerotic disease, but their
relation with subclinical coronary atherosclerosis is unclear. This study aimed to identify …