User profiles for Habtom W. Ressom

Habtom Ressom

Professor of Oncology at Georgetown University and Scientific Director at OmicsCraft LLC
Verified email at georgetown.edu
Cited by 7988

LC-MS-based metabolomics

B Zhou, JF Xiao, L Tuli, HW Ressom - Molecular BioSystems, 2012 - pubs.rsc.org
Metabolomics aims at identification and quantitation of small molecules involved in metabolic
reactions. LC-MS has enjoyed a growing popularity as the platform for metabolomic …

The properties of high-dimensional data spaces: implications for exploring gene and protein expression data

R Clarke, HW Ressom, A Wang, J Xuan, MC Liu… - Nature reviews …, 2008 - nature.com
High-throughput genomic and proteomic technologies are widely used in cancer research
to build better predictive models of diagnosis, prognosis and therapy, to identify and …

Metabolite identification and quantitation in LC-MS/MS-based metabolomics

JF Xiao, B Zhou, HW Ressom - TrAC Trends in Analytical Chemistry, 2012 - Elsevier
Metabolomics aims at detection and quantitation of all metabolites in biological samples.
The presence of metabolites with a wide variety of physicochemical properties and different …

Progenitor/stem cells give rise to liver cancer due to aberrant TGF-β and IL-6 signaling

…, C Li, CX Deng, SC Mueller, HW Ressom… - Proceedings of the …, 2008 - pnas.org
Cancer stem cells (CSCs) are critical for the initiation, propagation, and treatment resistance
of multiple cancers. Yet functional interactions between specific signaling pathways in solid …

Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis

HW Ressom, JF Xiao, L Tuli, RS Varghese, B Zhou… - Analytica chimica …, 2012 - Elsevier
… Author links open overlay panel Habtom W. Ressom a , Jun Feng Xiao a , Leepika Tuli a ,
Rency S. Varghese a , Bin Zhou a , Tsung-Heng Tsai a , Mohammad R. Nezami Ranjbar a , Yi …

LC–MS based serum metabolomics for identification of hepatocellular carcinoma biomarkers in Egyptian cohort

…, MG Tadesse, DH Ziada, HW Ressom - Journal of proteome …, 2012 - ACS Publications
Although hepatocellular carcinoma (HCC) has been subjected to continuous investigation
and its symptoms are well-known, early stage diagnosis of this disease remains difficult and …

An early response regulatory cluster induced by low temperature and hydrogen peroxide in seedlings of chilling-tolerant japonica rice

C Cheng, KY Yun, HW Ressom, B Mohanty, VB Bajic… - BMC genomics, 2007 - Springer
Background Plants respond to low temperature through an intricately coordinated
transcriptional network. The CBF/DREB-regulated network of genes has been shown to play a …

Detection of hepatocellular carcinoma using glycomic analysis

R Goldman, HW Ressom, RS Varghese… - Clinical cancer …, 2009 - aacrjournals.org
Purpose: Hepatocellular carcinoma (HCC) represents an increasing health problem in the
United States. Serum α-fetoprotein, the currently used clinical marker, is elevated in only ∼60…

LC–MS based detection of differential protein expression

L Tuli, HW Ressom - Journal of proteomics & bioinformatics, 2009 - pmc.ncbi.nlm.nih.gov
While several techniques are available in proteomics, LC-MS based analysis of complex
protein/peptide mixtures has turned out to be a mainstream analytical technique for quantitative …

The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer

…, A Cheema, R Varghese, HW Ressom… - Cell Death & …, 2018 - nature.com
Therapy resistance represents a clinical challenge for advanced non-small cell lung cancer (NSCLC),
which still remains an incurable disease. There is growing evidence that cancer-…