Huntington's disease (HD) is an autosomal dominant neurodegenerative disease. It is caused
by the expansion of the CAG trinucleotide repeat sequence in the HTT gene. HD mainly …

The metabolomic profile of aging is complex. Here, we analyse 325 nuclear magnetic resonance
(NMR) biomarkers from 250,341 UK Biobank participants, identifying 54 representative …

This study aimed to determine the mutational spectrum of familial Parkinson’s disease and
sporadic early-onset Parkinson’s disease (sEOPD) in a mainland Chinese population and the …

Image segmentation is an important application of polarimetric synthetic aperture radar. This
study aimed to create an 11-layer deep convolutional neural network for this task. The Pauli …

Pathological brain detection is an automated computer-aided diagnosis for brain images.
This study provides a novel method to achieve this goal.We first used synthetic minority …

De novo mutations (DNMs) significantly contribute to sporadic diseases, particularly in
neuropsychiatric disorders. Whole-exome sequencing (WES) and whole-genome sequencing (…

Pathological brain detection by computer vision is now attracting intense attentions from
academic fields. Nevertheless, most of recent methods suffer from low-accuracy. This study …

(Aim) Alcohol use disorder may put health at risk and cause serious health problems. It is of
increasing importance to identify alcohol use disorder as early as possible. (Method) This …

A failure of adaptive inference—misinterpreting available sensory information for
appropriate perception and action—is at the heart of clinical manifestations of schizophrenia, …

The aim of this study was to identify differences in functional and effective brain connectivity
between persons who stutter (PWS) and typically developing (TD) fluent speakers, and to …