THE Ets family of transcription factors, of which there are now about 35 members 1,2 , regulate
gene expression during growth and development. They share a conserved domain of …

Diverse guanine-rich RNAs and DNAs that fold to form guanine quadruplexes are known to
form tight complexes with Fe(III) heme. We show here that a wide variety of such complexes …

Transcription factors belonging to the ets family regulate gene expression and share a
conserved ETS DNA-binding domain that binds to the core sequence 5′-(C/A)GGA(A/T)-3′. …

PU.1 is an ets family transcription factor that is expressed specifically in hematopoietic lineages.
Through gene disruption studies in mice we have previously shown that the expression …

A new protein domain was found in several proteins involved in apoptosis, inflammation,
cancer and immune responses. Its location within these proteins and predicted fold suggests …

InterFeron-γ Inducible protein 16 (IFI16) belongs to the interferon inducible HIN200 protein
family that contains transcriptional regulators linked to cell cycle regulation and differentiation…

Self-aggregates of low density lipoprotein (LDL) are taken up and degraded more rapidly by
macrophages than is native LDL. That enhanced uptake is attributable in part to …

Motivation: Two proteins can have a similar 3-dimensional structure and biological function,
but have sequences sufficiently different that traditional protein sequence comparison …

The PU.1 transcription factor is a member of the ets gene family of regulatory proteins. These
molecules play a role in normal development and also have been implicated in malignant …

Wilms tumor (WT) is the second most common solid abdominal tumor in children. Surgical
resection has been established as a fundamental treatment approach with low morbidity rates. …