[HTML][HTML] Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes

E Lagoutte, S Mimoun, M Andriamihaja… - … et Biophysica Acta (BBA …, 2010 - Elsevier
Sulfide (H 2 S) is an inhibitor of mitochondrial cytochrome oxidase comparable to cyanide. In
this study, poisoning of cells was observed with sulfide concentrations above 20µM. Sulfide …

Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion

…, A Yamada, A Williart, C Lodillinsky, E Lagoutte… - Cell, 2021 - cell.com
Although mutations leading to a compromised nuclear envelope cause diseases such as
muscular dystrophies or accelerated aging, the consequences of mechanically induced …

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

…, A Castro-Castro, M Irondelle, E Lagoutte… - Journal of Cell …, 2013 - rupress.org
Remodeling of the extracellular matrix by carcinoma cells during metastatic dissemination
requires formation of actin-based protrusions of the plasma membrane called invadopodia, …

p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer

…, L Fuhrmann, J Cyrta, M Irondelle, E Lagoutte… - Oncogene, 2016 - nature.com
The transition of ductal carcinoma in situ (DCIS) to invasive breast carcinoma requires
tumor cells to cross the basement membrane (BM). However, mechanisms underlying BM …

Control of MT1-MMP transport by atypical PKC during breast-cancer progression

…, P Monteiro, M Irondelle, E Lagoutte… - Proceedings of the …, 2014 - National Acad Sciences
Dissemination of carcinoma cells requires the pericellular degradation of the extracellular
matrix, which is mediated by membrane type 1-matrix metalloproteinase (MT1-MMP). In this …

[HTML][HTML] LIMK regulates tumor-cell invasion and matrix degradation through tyrosine phosphorylation of MT1-MMP

E Lagoutte, C Villeneuve, L Lafanechère, CM Wells… - Scientific reports, 2016 - nature.com
During their metastatic spread, cancer cells need to remodel the extracellular matrix in order
to migrate through stromal compartments adjacent to the primary tumor. Dissemination of …

Wafer level thin film encapsulation for MEMS

C Gillot, JL Pornin, A Arnaud, E Lagoutte… - 2005 7th Electronic …, 2005 - ieeexplore.ieee.org
Because they have moving parts, or because they need to work in a specific atmosphere (vacuum,
inert gas,...), microelectromechanical systems (MEMS) are not compatible with …

aPKCi triggers basal extrusion of luminal mammary epithelial cells by tuning contractility and vinculin localization at cell junctions

C Villeneuve, E Lagoutte, L De Plater… - Proceedings of the …, 2019 - National Acad Sciences
Metastasis is the main cause of cancer-related deaths. How a single oncogenic cell evolves
within highly organized epithelium is still unknown. Here, we found that the overexpression …

Wafer level thin film encapsulation for BAW RF MEMS

…, C Gillot, G Parat, F Jacquet, E Lagoutte… - … 57th Electronic …, 2007 - ieeexplore.ieee.org
The BAW (Bulk acoustic Wave) RF filters that are used in mobile phone application are
composed of pair of piezo electrical resonators which need an air gap above them to operate. …

Master regulators in primary skin fibroblast fate reprogramming in a human ex vivo model of chronic wounds

M Noizet, E Lagoutte, M Gratigny… - Wound Repair and …, 2016 - Wiley Online Library
Fibroblasts are important players in regulating tissue homeostasis. In the dermis, they are
involved in wound healing where they differentiate into contractile myofibroblasts leading to …