User profiles for Angel Yu
Angel YuMIT Verified email at alum.mit.edu Cited by 36 |
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system
The type III secretion system (T3SS) is a macromolecular 'injectisome' that allows bacterial
pathogens to transport virulence proteins into the eukaryotic host cell. This macromolecular …
pathogens to transport virulence proteins into the eukaryotic host cell. This macromolecular …
The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2α and IRE1α/XBP-1 in colorectal cancer
Therapy-refractory disease is one of the main contributors of treatment failure in cancer. In
colorectal cancer (CRC), SPARC can function as a sensitizer to conventional chemotherapy …
colorectal cancer (CRC), SPARC can function as a sensitizer to conventional chemotherapy …
A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly
…, RA Pfuetzner, HB Felise, M Vuckovic, AC Yu… - PLoS …, 2013 - journals.plos.org
The T3SS injectisome is a syringe-shaped macromolecular assembly found in pathogenic
Gram-negative bacteria that allows for the direct delivery of virulence effectors into host cells. …
Gram-negative bacteria that allows for the direct delivery of virulence effectors into host cells. …
Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53‐mediated cellular senescence
Dysregulation of nucleophosmin 1 (NPM1) has been found in numerous solid and hematological
malignancies. Our previous meta‐analysis of colorectal cancer (CRC) high throughput …
malignancies. Our previous meta‐analysis of colorectal cancer (CRC) high throughput …
Inhibition of nucleophosmin 1 suppresses colorectal cancer tumor growth of patient-derived xenografts via activation of p53 and inhibition of AKT
The nucleophosmin 1 (NPM1) protein is frequently overexpressed in various cancers
compared to normal tissues and represents a potential biomarker for maliganancy. However, its …
compared to normal tissues and represents a potential biomarker for maliganancy. However, its …
Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases
ACY Yu, G Volkers, SAK Jongkees, LJ Worrall… - …, 2022 - academic.oup.com
Propionibacterium acnes, though generally considered part of the normal flora of human
skin, is an opportunistic pathogen associated with acne vulgaris as well as other diseases, …
skin, is an opportunistic pathogen associated with acne vulgaris as well as other diseases, …
Distributed MCMC inference in Dirichlet process mixture models using Julia
Due to the increasing availability of large data sets, the need for general-purpose massively-parallel
analysis tools become ever greater. In unsupervised learning, Bayesian …
analysis tools become ever greater. In unsupervised learning, Bayesian …
Rediscovered Voices: Chinese Immigrants and Angel Island
CY Yu - Amerasia Journal, 1977 - Taylor & Francis
The Cantonese immigrant stood on the bench by the grated window and carefully carved out
the words he had first written with a brush. Other immigrants, frustrated by long detention in …
the words he had first written with a brush. Other immigrants, frustrated by long detention in …
EscE and EscG are cochaperones for the type III needle protein EscF of enteropathogenic Escherichia coli
…, D Setiaputra, R Scholz, W Deng, ACY Yu… - Journal of …, 2013 - journals.asm.org
Type III secretion systems (T3SSs) are central virulence mechanisms used by a variety of
Gram-negative bacteria to inject effector proteins into host cells. The needle polymer is an …
Gram-negative bacteria to inject effector proteins into host cells. The needle polymer is an …
[PDF][PDF] Angel: a new large-scale machine learning system
… , we introduce the modules of Angel, and how Angel executes ML applications. … Angel by
comparing Angel with Spark and Petuum using various ML algorithms. We also compare Angel …
comparing Angel with Spark and Petuum using various ML algorithms. We also compare Angel …