User profiles for Alaptagin Khan
 | Alaptagin KhanInstructor in Psychiatry, Harvard Medical School Verified email at mclean.harvard.edu Cited by 2014 |
International meta-analysis of PTSD genome-wide association studies identifies sex-and ancestry-specific genetic risk loci
The risk of posttraumatic stress disorder (PTSD) following trauma is heritable, but robust
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD …
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD …
Childhood maltreatment, depression, and suicidal ideation: critical importance of parental and peer emotional abuse during developmental sensitive periods in males …
A Khan, HC McCormack, EA Bolger… - Frontiers in …, 2015 - frontiersin.org
Background: The adverse childhood experience (ACE) study found that risk for depression
increased as a function of number of types of childhood maltreatment, and interpret this as a …
increased as a function of number of types of childhood maltreatment, and interpret this as a …
Differential effects of childhood neglect and abuse during sensitive exposure periods on male and female hippocampus
The hippocampus is a highly stress susceptible structure and hippocampal abnormalities
have been reported in a host of psychiatric disorders including major depression and post-…
have been reported in a host of psychiatric disorders including major depression and post-…
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability
than most other psychiatric disorders. The contribution to biological understanding from …
than most other psychiatric disorders. The contribution to biological understanding from …
Potential sensitive period effects of maltreatment on amygdala, hippocampal and cortical response to threat
Childhood maltreatment is a leading risk factor for psychopathology, though it is unclear
why some develop risk averse disorders, such as anxiety and depression, and others risk-taking …
why some develop risk averse disorders, such as anxiety and depression, and others risk-taking …
Childhood maltreatment is associated with alteration in global network fiber-tract architecture independent of history of depression and anxiety
Childhood maltreatment is a major risk factor for psychopathology. It is also associated with
alterations in the network architecture of the brain, which we hypothesized may play a …
alterations in the network architecture of the brain, which we hypothesized may play a …
Susceptibility or resilience to maltreatment can be explained by specific differences in brain network architecture
Background Childhood maltreatment is a major risk factor for psychopathology. However,
some maltreated individuals appear remarkably resilient to the psychiatric effects while …
some maltreated individuals appear remarkably resilient to the psychiatric effects while …
Genomic influences on self-reported childhood maltreatment
Childhood maltreatment is highly prevalent and serves as a risk factor for mental and physical
disorders. Self-reported childhood maltreatment appears heritable, but the specific genetic …
disorders. Self-reported childhood maltreatment appears heritable, but the specific genetic …
Effects of a mindfulness-based intervention on self-compassion and psychological health among young adults with a history of childhood maltreatment
Background Individuals who were maltreated during childhood are faced with increased risks
for developing various psychological symptoms that are particularly resistant to traditional …
for developing various psychological symptoms that are particularly resistant to traditional …
[HTML][HTML] Enhancing discovery of genetic variants for posttraumatic stress disorder through integration of quantitative phenotypes and trauma exposure information
Background Posttraumatic stress disorder (PTSD) is heritable and a potential consequence
of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD …
of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD …