User profiles for Austen Curtin

Austen Curtin

Icahn School of Medicine
Verified email at mssm.edu
Cited by 307

Dynamical features in fetal and postnatal zinc-copper metabolic cycles predict the emergence of autism spectrum disorder

P Curtin, C Austin, A Curtin, C Gennings, M Arora… - Science …, 2018 - science.org
Metals are critical to neurodevelopment, and dysregulation in early life has been documented
in autism spectrum disorder (ASD). However, underlying mechanisms and biochemical …

Altered periodic dynamics in the default mode network in autism and attention-deficit/hyperactivity disorder

P Curtin, J Neufeld, A Curtin, M Arora, S Bölte - Biological psychiatry, 2022 - Elsevier
Background Altered resting-state functional connectivity in the default mode network (DMN)
is characteristic of both autism spectrum disorder (ASD) and attention-deficit/hyperactivity …

Recurrence quantification analysis to characterize cyclical components of environmental elemental exposures during fetal and postnatal development

P Curtin, A Curtin, C Austin, C Gennings… - PLoS …, 2017 - journals.plos.org
Environmental exposures to essential and toxic elements may alter health trajectories,
depending on the timing, intensity, and mixture of exposures. In epidemiologic studies, these …

Elemental dynamics in hair accurately predict future autism spectrum disorder diagnosis: an international multi-center study

…, P Curtin, M Arora, A Reichenberg, A Curtin… - Journal of Clinical …, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental condition diagnosed in approximately
2% of children. Reliance on the emergence of clinically observable behavioral patterns …

Dynamical properties of elemental metabolism distinguish attention deficit hyperactivity disorder from autism spectrum disorder

C Austin, P Curtin, A Curtin, C Gennings… - Translational …, 2019 - nature.com
Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are
neurodevelopmental conditions of overlapping etiologies and phenotypes. For ASD, we recently …

Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis

P Curtin, C Austin, A Curtin, C Gennings… - PLoS Computational …, 2020 - journals.plos.org
Evolutionarily conserved mechanisms maintain homeostasis of essential elements, and are
believed to be highly time-variant. However, current approaches measure elemental …

Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth

K Wahlberg, M Arora, A Curtin, P Curtin, RO Wright… - Neurotoxicology, 2018 - Elsevier
Background Manganese (Mn) is an essential metal that can become neurotoxic at elevated
levels with negative consequences on neurodevelopment. We have evaluated the influence …

Associations between elemental metabolic dynamics and default mode network functional connectivity are altered in autism

P Curtin, J Neufeld, A Curtin, C Austin… - Journal of clinical …, 2023 - mdpi.com
Autism is a neurodevelopmental condition associated with atypical social communication,
cognitive, and sensory faculties. Recent advances in exposure biology suggest that …

Network Dynamics in Elemental Assimilation and Metabolism

A Curtin, C Austin, A Giuliani, M Ruiz Marín… - Entropy, 2021 - mdpi.com
Metabolism and physiology frequently follow non-linear rhythmic patterns which are reflected
in concepts of homeostasis and circadian rhythms, yet few biomarkers are studied as …

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