User profiles for Austen Curtin
Austen CurtinIcahn School of Medicine Verified email at mssm.edu Cited by 307 |
Dynamical features in fetal and postnatal zinc-copper metabolic cycles predict the emergence of autism spectrum disorder
Metals are critical to neurodevelopment, and dysregulation in early life has been documented
in autism spectrum disorder (ASD). However, underlying mechanisms and biochemical …
in autism spectrum disorder (ASD). However, underlying mechanisms and biochemical …
Altered periodic dynamics in the default mode network in autism and attention-deficit/hyperactivity disorder
Background Altered resting-state functional connectivity in the default mode network (DMN)
is characteristic of both autism spectrum disorder (ASD) and attention-deficit/hyperactivity …
is characteristic of both autism spectrum disorder (ASD) and attention-deficit/hyperactivity …
Recurrence quantification analysis to characterize cyclical components of environmental elemental exposures during fetal and postnatal development
Environmental exposures to essential and toxic elements may alter health trajectories,
depending on the timing, intensity, and mixture of exposures. In epidemiologic studies, these …
depending on the timing, intensity, and mixture of exposures. In epidemiologic studies, these …
Elemental dynamics in hair accurately predict future autism spectrum disorder diagnosis: an international multi-center study
Autism spectrum disorder (ASD) is a neurodevelopmental condition diagnosed in approximately
2% of children. Reliance on the emergence of clinically observable behavioral patterns …
2% of children. Reliance on the emergence of clinically observable behavioral patterns …
Dynamical properties of elemental metabolism distinguish attention deficit hyperactivity disorder from autism spectrum disorder
Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are
neurodevelopmental conditions of overlapping etiologies and phenotypes. For ASD, we recently …
neurodevelopmental conditions of overlapping etiologies and phenotypes. For ASD, we recently …
Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis
Evolutionarily conserved mechanisms maintain homeostasis of essential elements, and are
believed to be highly time-variant. However, current approaches measure elemental …
believed to be highly time-variant. However, current approaches measure elemental …
Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth
Background Manganese (Mn) is an essential metal that can become neurotoxic at elevated
levels with negative consequences on neurodevelopment. We have evaluated the influence …
levels with negative consequences on neurodevelopment. We have evaluated the influence …
Associations between elemental metabolic dynamics and default mode network functional connectivity are altered in autism
Autism is a neurodevelopmental condition associated with atypical social communication,
cognitive, and sensory faculties. Recent advances in exposure biology suggest that …
cognitive, and sensory faculties. Recent advances in exposure biology suggest that …
Network Dynamics in Elemental Assimilation and Metabolism
Metabolism and physiology frequently follow non-linear rhythmic patterns which are reflected
in concepts of homeostasis and circadian rhythms, yet few biomarkers are studied as …
in concepts of homeostasis and circadian rhythms, yet few biomarkers are studied as …
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