Background Safe and effective vaccines are urgently needed to end the COVID-19 pandemic
caused by SARS-CoV-2 infection. We aimed to assess the preliminary safety, tolerability, …

As one of the most induced genes in activated macrophages, immune-responsive gene 1 (IRG1)
encodes a mitochondrial metabolic enzyme catalysing the production of itaconic acid (…

Melatonin has beneficial effects against early brain injury (EBI) by modulating cerebral oxidative
stress after experimental subarachnoid hemorrhage (SAH); however, few investigations …

Plant stoichiometric coupling among all elements is fundamental to maintaining growth‐related
ecosystem functions. However, our understanding of nutrient balance in response to …

The current research aimed to investigate the role of hypoxia-inducible factor-1α (HIF-1α),
aquaporin-4 (AQP-4), and matrix metalloproteinase-9 (MMP-9) in blood–brain barrier (BBB) …

This study is to investigate the role of lipid transfer protein (LTP1) gene of wheat (Triticum
aestivum L.) in powdery mildew (Blumeria graminis f.sp. tritici, Bgt) resistance. A pair of primers …

Objectives Investigating the antipulmonary fibrosis effect of mangiferin from Mangifera
indica and the possible molecular mechanism. Methods In vivo, bleomycin (BLM)-induced …

Conventional methods for assessing the impacts of climate change on crop production are
often unable to account for the impacts of extreme weather events and therefore …

Till date, developing flexible poly(vinylidene fluoride) (PVDF) based nanocomposites with
high piezoelectric performance is of great interest for constructing sensors, transducers and …

Several epidermal growth factor receptor (EGFR) proteolysis-targeting chimeras (PROTACs),
including MS39 and MS154 developed by us, have been reported to effectively degrade …