User profiles for Max J. H. Witjes

Max Witjes

Professor Oral & Maxillofacial Surgery, University Medical Center Groningen
Verified email at umcg.nl
Cited by 7864

Extra-intestinal manifestations of familial adenomatous polyposis

…, J de Vries, JH Kleibeuker, MJH Witjes… - Annals of surgical …, 2008 - Springer
Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited disorder, which
results from a germ line mutation in the APC (adenomatous polyposis coli) gene. FAP is …

Intraoperative imaging in pathology-assisted surgery

…, V Ntziachristos, PJ van der Zaag, MJH Witjes… - Nature biomedical …, 2022 - nature.com
The pathological assessment of surgical specimens during surgery can reduce the
incidence of positive resection margins, which otherwise can result in additional surgeries or …

A systematic review of functional outcome and quality of life following reconstruction of maxillofacial defects using vascularized free fibula flaps and dental …

…, RH Schepers, PMN Werker, MJH Witjes… - Journal of Plastic …, 2016 - Elsevier
Background Reconstruction and oral rehabilitation of segmental maxillofacial defects resulting
from ablative surgery is commonly achieved by osteocutaneous vascularized free fibula (…

Human salivary gland stem cells functionally restore radiation damaged salivary glands

…, MA Stokman, D van Gosliga, E Zwart, MJH Witjes… - Stem …, 2016 - academic.oup.com
Adult stem cells are often touted as therapeutic agents in the regenerative medicine field,
however data detailing both the engraftment and functional capabilities of solid tissue derived …

EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial

…, WB Nagengast, GM van Dam, MJH Witjes - Nature …, 2023 - nature.com
Inadequate surgical margins occur frequently in oral squamous cell carcinoma surgery.
Fluorescence molecular imaging (FMI) has been explored for intraoperative margin assessment, …

Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery

…, JP Hartung, J Gao, BD Sumer, MJH Witjes… - Nature …, 2020 - nature.com
Cancer cell metabolism leads to a uniquely acidic microenvironment in solid tumors, but
exploiting the labile extracellular pH differences between cancer and normal tissues for clinical …

Autofluorescence and diffuse reflectance spectroscopy for oral oncology

DCG De Veld, M Skurichina, MJH Witjes… - Lasers in Surgery …, 2005 - Wiley Online Library
Background and Objectives Autofluorescence and diffuse reflectance spectroscopy have
been used separately and combined for tissue diagnostics. Previously, we assessed the value …

Autofluorescence characteristics of healthy oral mucosa at different anatomical sites

DCG de Veld, M Skurichina, MJH Witjes… - Lasers in Surgery …, 2003 - Wiley Online Library
Background and Objectives Autofluorescence spectroscopy is a promising tool for oral cancer
detection. Its reliability might be improved by using a reference database of spectra from …

A clinicopathological study and prognostic factor analysis of 177 salivary duct carcinoma patients from T he N etherlands

…, LA van der Velden, MJH Witjes… - … journal of cancer, 2018 - Wiley Online Library
Salivary duct carcinoma (SDC) is a subtype of salivary gland cancer with a dismal prognosis
and a need for better prognostication and novel treatments. The aim of this national cohort …

[HTML][HTML] Impact of sarcopenia on survival and late toxicity in head and neck cancer patients treated with radiotherapy

…, SF Oosting, GB Halmos, MJH Witjes… - Radiotherapy and …, 2020 - Elsevier
Background and purpose Sarcopenia is emerging as an adverse prognostic factor for
survival and complication risk in cancer patients. This study aims to determine the impact of …