User profiles for Matthew Falk
Matthew S Falk MDNuclear Medicine Physician, VA Northern California Healthcare System Verified email at va.gov Cited by 403 |
Acquired Resistance to Crizotinib from a Mutation in CD74–ROS1
…, A Brooun, L Friboulet, D Huang, MD Falk… - … England Journal of …, 2013 - Mass Medical Soc
<p id="p001">Crizotinib, an inhibitor of anaplastic lymphoma kinase (ALK), has also recently
shown efficacy in the treatment of lung cancers with <italic>ROS1</italic> translocations. …
shown efficacy in the treatment of lung cancers with <italic>ROS1</italic> translocations. …
Controlling signaling with a specifically designed Gi-coupled receptor
P Coward, HG Wada, MS Falk… - Proceedings of the …, 1998 - National Acad Sciences
We are developing a system to control G protein signaling in vivo to regulate a broad range
of physiologic responses. Our system utilizes G protein-coupled peptide receptors …
of physiologic responses. Our system utilizes G protein-coupled peptide receptors …
PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations
…, SRP McDonnell, P Jiang, MD Falk… - Proceedings of the …, 2015 - National Acad Sciences
Oncogenic c-ros oncogene1 (ROS1) fusion kinases have been identified in a variety of
human cancers and are attractive targets for cancer therapy. The MET/ALK/ROS1 inhibitor …
human cancers and are attractive targets for cancer therapy. The MET/ALK/ROS1 inhibitor …
Factors affecting timely completion of a PhD: a complex systems approach
J Pitchforth, S Beames, A Thomas, M Falk… - Journal of the …, 2012 - eprints.qut.edu.au
Completing a PhD on time is a complex process, influenced by many interacting factors. In
this paper we take a Bayesian Network approach to analyzing the factors perceived to be …
this paper we take a Bayesian Network approach to analyzing the factors perceived to be …
Monitoring resistance to phosphine in the lesser grain borer, Rhyzopertha dominica, in Australia: a national analysis of trends, storage types and geography in relation …
PJ Collins, MG Falk, MK Nayak, RN Emery… - Journal of Stored …, 2017 - Elsevier
Data on incidence of resistance to phosphine over the last 20 years and factors associated
with insect sample collection are stored in the Australian Grain Insect Resistance Database. …
with insect sample collection are stored in the Australian Grain Insect Resistance Database. …
An analysis of trends, frequencies and factors influencing the development of resistance to phosphine in the red flour beetle Tribolium castaneum (Herbst) in Australia
MK Nayak, MG Falk, RN Emery, PJ Collins… - Journal of Stored …, 2017 - Elsevier
Although resistance to phosphine, the key disinfestant used worldwide in the stored grain
environment has been an ongoing industry issue, studies on its trend over large geographic …
environment has been an ongoing industry issue, studies on its trend over large geographic …
Exposure to particles from laser printers operating within office workplaces
…, L Morawska, C He, R Jayaratne, M Falk… - … science & technology, 2011 - ACS Publications
While recent research has provided valuable information as to the composition of laser printer
particles, their formation mechanisms, and explained why some printers are emitters while …
particles, their formation mechanisms, and explained why some printers are emitters while …
Structure-based drug design and synthesis of PI3Kα-selective inhibitor (PF-06843195)
…, CD Almaden, S Bagrodia, MD Falk… - Journal of medicinal …, 2020 - ACS Publications
The phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) signaling
pathway is a frequently dysregulated pathway in human cancer, and PI3Kα is one of the most …
pathway is a frequently dysregulated pathway in human cancer, and PI3Kα is one of the most …
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells
SM Stanford, D Krishnamurthy, MD Falk… - Journal of medicinal …, 2011 - ACS Publications
The lymphoid tyrosine phosphatase LYP, encoded by the PTPN22 gene, is a critical
regulator of signaling in T cells and recently emerged as a candidate target for therapy of …
regulator of signaling in T cells and recently emerged as a candidate target for therapy of …
Vertical particle concentration profiles around urban office buildings
…, C He, L Morawska, LD Knibbs, M Falk - … Chemistry and Physics, 2012 - acp.copernicus.org
Despite its role in determining both indoor and outdoor human exposure to anthropogenic
particles, there is limited information describing vertical profiles of particle concentrations in …
particles, there is limited information describing vertical profiles of particle concentrations in …