User profiles for Matt Sinclair
A Gram-negative-selective antibiotic that spares the gut microbiome
Infections caused by Gram-negative pathogens are increasingly prevalent and are typically
treated with broad-spectrum antibiotics, resulting in disruption of the gut microbiome and …
treated with broad-spectrum antibiotics, resulting in disruption of the gut microbiome and …
The gem5 simulator: Version 20.0+
…, J Setoain, B Shingarov, MD Sinclair… - arXiv preprint arXiv …, 2020 - arxiv.org
The open-source and community-supported gem5 simulator is one of the most popular tools
for computer architecture research. This simulation infrastructure allows researchers to …
for computer architecture research. This simulation infrastructure allows researchers to …
[HTML][HTML] Automated cardiovascular magnetic resonance image analysis with fully convolutional networks
Background Cardiovascular resonance (CMR) imaging is a standard imaging modality for
assessing cardiovascular diseases (CVDs), the leading cause of death globally. CMR …
assessing cardiovascular diseases (CVDs), the leading cause of death globally. CMR …
Ensembles of multiple models and architectures for robust brain tumour segmentation
Deep learning approaches such as convolutional neural nets have consistently outperformed
previous methods on challenging tasks such as dense, semantic segmentation. However, …
previous methods on challenging tasks such as dense, semantic segmentation. However, …
Semi-supervised learning for network-based cardiac MR image segmentation
Training a fully convolutional network for pixel-wise (or voxel-wise) image segmentation
normally requires a large number of training images with corresponding ground truth label maps…
normally requires a large number of training images with corresponding ground truth label maps…
[HTML][HTML] A novel porous mechanical framework for modelling the interaction between coronary perfusion and myocardial mechanics
The strong coupling between the flow in coronary vessels and the mechanical deformation
of the myocardial tissue is a central feature of cardiac physiology and must therefore be …
of the myocardial tissue is a central feature of cardiac physiology and must therefore be …
Consumer intervention mapping—A tool for designing future product strategies within circular product service systems
Re-distributed manufacturing presents a number of opportunities and challenges for New
Product Development in a future Circular Economy. It has been argued that small-scale, …
Product Development in a future Circular Economy. It has been argued that small-scale, …
Fully automated, quality-controlled cardiac analysis from CMR: validation and large-scale application to characterize cardiac function
Objectives This study sought to develop a fully automated framework for cardiac function
analysis from cardiac magnetic resonance (CMR), including comprehensive quality control (QC…
analysis from cardiac magnetic resonance (CMR), including comprehensive quality control (QC…
T3: Transparent tracking & triggering for fine-grained overlap of compute & collectives
Large Language Models increasingly rely on distributed techniques for their training and
inference. These techniques require communication across devices which can reduce scaling …
inference. These techniques require communication across devices which can reduce scaling …
Lost in abstraction: Pitfalls of analyzing GPUs at the intermediate language level
Modern GPU frameworks use a two-phase compilation approach. Kernels written in a high-level
language are initially compiled to an implementation agnostic intermediate language (IL…
language are initially compiled to an implementation agnostic intermediate language (IL…