User profiles for Matt Sinclair

Matthew Sinclair - Verified email at heartflow.com - Cited by 5814
Matthew D. Sinclair - Verified email at cs.wisc.edu - Cited by 1451
Matt Sinclair - Verified email at napier.ac.uk - Cited by 314

A Gram-negative-selective antibiotic that spares the gut microbiome

KA Muñoz, RJ Ulrich, AK Vasan, M Sinclair, PC Wen… - Nature, 2024 - nature.com
Infections caused by Gram-negative pathogens are increasingly prevalent and are typically
treated with broad-spectrum antibiotics, resulting in disruption of the gut microbiome and …

The gem5 simulator: Version 20.0+

…, J Setoain, B Shingarov, MD Sinclair… - arXiv preprint arXiv …, 2020 - arxiv.org
The open-source and community-supported gem5 simulator is one of the most popular tools
for computer architecture research. This simulation infrastructure allows researchers to …

[HTML][HTML] Automated cardiovascular magnetic resonance image analysis with fully convolutional networks

W Bai, M Sinclair, G Tarroni, O Oktay, M Rajchl… - Journal of …, 2018 - Elsevier
Background Cardiovascular resonance (CMR) imaging is a standard imaging modality for
assessing cardiovascular diseases (CVDs), the leading cause of death globally. CMR …

Ensembles of multiple models and architectures for robust brain tumour segmentation

…, W Bai, E Ferrante, S McDonagh, M Sinclair… - … Sclerosis, Stroke and …, 2018 - Springer
Deep learning approaches such as convolutional neural nets have consistently outperformed
previous methods on challenging tasks such as dense, semantic segmentation. However, …

Semi-supervised learning for network-based cardiac MR image segmentation

W Bai, O Oktay, M Sinclair, H Suzuki, M Rajchl… - … Image Computing and …, 2017 - Springer
Training a fully convolutional network for pixel-wise (or voxel-wise) image segmentation
normally requires a large number of training images with corresponding ground truth label maps…

[HTML][HTML] A novel porous mechanical framework for modelling the interaction between coronary perfusion and myocardial mechanics

…, R Chabiniok, E Hyde, DA Nordsletten, M Sinclair… - Journal of …, 2012 - Elsevier
The strong coupling between the flow in coronary vessels and the mechanical deformation
of the myocardial tissue is a central feature of cardiac physiology and must therefore be …

Consumer intervention mapping—A tool for designing future product strategies within circular product service systems

M Sinclair, L Sheldrick, M Moreno, E Dewberry - Sustainability, 2018 - mdpi.com
Re-distributed manufacturing presents a number of opportunities and challenges for New
Product Development in a future Circular Economy. It has been argued that small-scale, …

Fully automated, quality-controlled cardiac analysis from CMR: validation and large-scale application to characterize cardiac function

B Ruijsink, E Puyol-Antón, I Oksuz, M Sinclair… - Cardiovascular …, 2020 - jacc.org
Objectives This study sought to develop a fully automated framework for cardiac function
analysis from cardiac magnetic resonance (CMR), including comprehensive quality control (QC…

T3: Transparent tracking & triggering for fine-grained overlap of compute & collectives

…, S Aga, M Islam, N Jayasena, MD Sinclair - Proceedings of the 29th …, 2024 - dl.acm.org
Large Language Models increasingly rely on distributed techniques for their training and
inference. These techniques require communication across devices which can reduce scaling …

Lost in abstraction: Pitfalls of analyzing GPUs at the intermediate language level

…, B Potter, S Puthoor, MD Sinclair… - … Symposium on High …, 2018 - ieeexplore.ieee.org
Modern GPU frameworks use a two-phase compilation approach. Kernels written in a high-level
language are initially compiled to an implementation agnostic intermediate language (IL…