Prevalence and risk factors of cerebral microbleeds: an update of the Rotterdam scan study

MMF Poels, MW Vernooij, MA Ikram, A Hofman… - Stroke, 2010 - ahajournals.org
Background and Purpose—We previously reported on the high prevalence of cerebral
microbleeds (CMBs) in community-dwelling people aged 60 years and older. Moreover, we found …

Cerebral microbleeds are associated with worse cognitive function: the Rotterdam Scan Study

MMF Poels, MA Ikram, A van der Lugt, A Hofman… - Neurology, 2012 - neurology.org
Objective: Cerebral microbleeds are frequently found in the general elderly population and
may reflect underlying vascular disease, but their role in cognitive function is unknown. …

Incidence of cerebral microbleeds in the general population: the Rotterdam Scan Study

MMF Poels, MA Ikram, A van der Lugt, A Hofman… - Stroke, 2011 - ahajournals.org
Background and Purpose— Cerebral microbleeds are frequently seen in the general elderly
population, but it is unknown at what rate they occur with aging and whether once present …

Arterial stiffness and cerebral small vessel disease: the Rotterdam Scan Study

MMF Poels, K Zaccai, GC Verwoert, MW Vernooij… - Stroke, 2012 - ahajournals.org
Background and Purpose— Aging and vascular risk factors contribute to arterial stiffening.
Increased arterial stiffness exposes the small vessels in the brain to abnormal flow pulsations …

Arterial stiffness, cognitive decline, and risk of dementia: the Rotterdam study

MMF Poels, M van Oijen, FUS Mattace-Raso… - Stroke, 2007 - ahajournals.org
Background and Purpose— Arterial stiffness is associated with an increased risk of myocardial
infarction and stroke, independent of classical vascular risk factors. Vascular factors and …

Serum lipid levels and the risk of intracerebral hemorrhage: the Rotterdam Study

RG Wieberdink, MMF Poels, MW Vernooij… - … , and vascular biology, 2011 - ahajournals.org
Objective— Low serum total cholesterol levels are associated with an increased risk of
symptomatic intracerebral hemorrhage and with presence of asymptomatic cerebral microbleeds. …

Total cerebral blood flow in relation to cognitive function: the Rotterdam Scan Study

MMF Poels, MA Ikram, MW Vernooij… - Journal of Cerebral …, 2008 - journals.sagepub.com
Cerebral hypoperfusion has been associated with worse cognitive function. We investigated
the association between cerebral blood flow and cognition and whether this association is …

Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study

DJ Mesker, MMF Poels, MA Ikram… - Archives of …, 2011 - jamanetwork.com
Objective To investigate the distribution of lobar microbleeds over the different lobes, taking
into account lobar volume and clustering effects of multiple microbleeds. Design Population-…

Prevalence, clinical management, and natural course of incidental findings on brain MR images: the population-based Rotterdam Scan Study

D Bos, MMF Poels, HHH Adams, S Akoudad… - Radiology, 2016 - pubs.rsna.org
Purpose To present an updated prevalence estimate for incidental findings on brain magnetic
resonance (MR) images and provide information on clinical relevance, including natural …

Assessment of cerebral small vessel disease predicts individual stroke risk

MMF Poels, EW Steyerberg, RG Wieberdink… - Journal of Neurology …, 2012 - jnnp.bmj.com
Background Despite several known risk factors it is still difficult to foresee who will develop a
stroke and who will not. Vascular brain damage, visualised with MRI, reflects how the brain …