Distinct dopaminergic control of the direct and indirect pathways in reward-based and avoidance learning behaviors

S Nakanishi, T Hikida, S Yawata - Neuroscience, 2014 - Elsevier
The nucleus accumbens (NAc) plays a pivotal role in reward and aversive learning and
learning flexibility. Outputs of the NAc are transmitted through two parallel routes termed the …

Aversive behavior induced by optogenetic inactivation of ventral tegmental area dopamine neurons is mediated by dopamine D2 receptors in the nucleus accumbens

T Danjo, K Yoshimi, K Funabiki… - Proceedings of the …, 2014 - National Acad Sciences
Dopamine (DA) transmission from the ventral tegmental area (VTA) is critical for controlling
both rewarding and aversive behaviors. The transient silencing of DA neurons is one of the …

Pathway-specific control of reward learning and its flexibility via selective dopamine receptors in the nucleus accumbens

S Yawata, T Yamaguchi, T Danjo… - Proceedings of the …, 2012 - National Acad Sciences
In the basal ganglia, inputs from the nucleus accumbens (NAc) are transmitted through both
direct and indirect pathways and control reward-based learning. In the NAc, dopamine (DA) …

Pathway-specific modulation of nucleus accumbens in reward and aversive behavior via selective transmitter receptors

T Hikida, S Yawata, T Yamaguchi… - Proceedings of the …, 2013 - National Acad Sciences
The basal ganglia–thalamocortical circuitry plays a central role in selecting actions that
achieve reward-seeking outcomes and avoid aversive ones. Inputs of the nucleus …

Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons

K Imamura, N Sahara, NM Kanaan, K Tsukita… - Scientific reports, 2016 - nature.com
Mutations in the gene MAPT encoding tau, a microtubules-associated protein, cause a
subtype of familial neurodegenerative disorder, known as frontotemporal lobar degeneration …

Relevance of iPSC-derived human PGC-like cells at the surface of embryoid bodies to prechemotaxis migrating PGCs

S Mitsunaga, J Odajima, S Yawata… - Proceedings of the …, 2017 - National Acad Sciences
Pluripotent stem cell-derived human primordial germ cell-like cells (hPGCLCs) provide
important opportunities to study primordial germ cells (PGCs). We robustly produced CD38+ …

Prenatal Exposure to Bisphenol A Disrupts Naturally Occurring Bimodal DNA Methylation at Proximal Promoter of fggy, an Obesity-Relevant Gene Encoding a …

JA Taylor, K Shioda, S Mitsunaga, S Yawata… - …, 2018 - academic.oup.com
Exposure of mammalian fetuses to endocrine disruptors can increase the risk of adult-onset
diseases. We previously showed that exposure of mouse fetuses to bisphenol A (BPA) …

Spatio‐temporal control of neural activity in vivo using fluorescence microendoscopy

Y Hayashi, Y Tagawa, S Yawata… - European Journal of …, 2012 - Wiley Online Library
Controlling neural activity with high spatio‐temporal resolution is desired for studying how
neural circuit dynamics control animal behavior. Conventional methods for manipulating …

[HTML][HTML] Local anesthetic systemic toxicity of levobupivacaine in erector spinae plane block

S Yawata, N Imamachi, S Sakura… - Korean Journal of …, 2021 - synapse.koreamed.org
The erector spinae plane block (ESPB) has been reported to have several complications.
However, there has been no report of local anesthetic systemic toxicity (LAST). Here, we …

MR imaging of Wallerian degeneration in the brainstem: temporal relationships.

Y Inoue, Y Matsumura, T Fukuda… - American journal …, 1990 - Am Soc Neuroradiology
Degeneration of the myelin sheath and axon distal to the most proximal site of axonal
interruption secondary to axonal disease has been called wallerian degeneration. On MR …