Cancer evolution at all stages is driven by both epigenetic abnormalities as well as genetic
alterations. Dysregulation of epigenetic control events may lead to abnormal patterns of …

The existence of subpopulations of cells in cancers with increased tumor-initiating capacities
and self-renewal potential, often termed" cancer stem cells," is a much discussed and key …

Purpose of Review. Transversus abdominis plane (TAP) block is a regional technique for
analgesia of the anterolateral abdominal wall. This review highlights the nomenclature …

Natural rewards and drugs of abuse can alter dopamine signaling, and ventral tegmental
area (VTA) dopaminergic neurons are known to fire action potentials tonically or phasically …

Reversal of promoter DNA hypermethylation and associated gene silencing is an attractive
cancer therapy approach. The DNA methylation inhibitors decitabine and azacitidine are …

Ventral tegmental area (VTA) dopamine neurons in the brain's reward circuit have a crucial
role in mediating stress responses,,,, including determining susceptibility versus resilience to …

Major depression is characterized by diverse debilitating symptoms that include
hopelessness and anhedonia. Dopamine neurons involved in reward and motivation …

The halophile Vibrio vulnificus is an etiologic agent of human mortality from seafood-borne
infections. We applied whole-genome sequencing and comparative analysis to investigate …

Phasic activation of dopaminergic neurons is associated with reward-predicting cues and
supports learning during behavioral adaptation. While noncontingent activation of …

Nosocomial infections caused by antibiotic-resistant Klebsiella pneumoniae are emerging
as a major health problem worldwide, while community-acquired K. pneumoniae infections …