In the last two years the Pfam database (http://pfam. xfam. org) has undergone a substantial
reorganisation to reduce the effort involved in making a release, thereby permitting more …

The EMBL-EBI provides free access to popular bioinformatics sequence analysis
applications as well as to a full-featured text search engine with powerful cross-referencing …

The last few years have witnessed significant changes in Pfam (https://pfam. xfam. org). The
number of families has grown substantially to a total of 17,929 in release 32.0. New …

Abstract The HMMER webserver [http://www. ebi. ac. uk/Tools/hmmer] is a free-to-use
service which provides fast searches against widely used sequence databases and profile …

Abstract InterPro (http://www. ebi. ac. uk/interpro/) is a freely available database used to
classify protein sequences into families and to predict the presence of important domains …

Abstract The InterPro database (http://www. ebi. ac. uk/interpro/) classifies protein
sequences into families and predicts the presence of functionally important domains and …

(WTCCC2) consortia is provided in the Supplementary Note online. Author Contributions
FC, ADB, CEMG, J. Kere., A. Reis, JNB and RCT oversaw cohort collection for both the …

Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting the
spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent …

To identify previously unknown genetic loci associated with fasting glucose concentrations,
we examined the leading association signals in ten genome-wide association scans …

The number and volume of cells in the blood affect a wide range of disorders including
cancer and cardiovascular, metabolic, infectious and immune conditions. We consider here …