Clinical trials in head injury

RK Narayan, ME Michel, B Ansell… - Journal of …, 2002 - liebertpub.com
Traumatic brain injury (TBI) remains a major public health problem globally. In the United
States the incidence of closed head injuries admitted to hospitals is conservatively estimated …

Patient age and outcome following severe traumatic brain injury: an analysis of 5600 patients

CWPM Hukkelhoven, EW Steyerberg… - Journal of …, 2003 - thejns.org
Object. Increasing age is associated with poorer outcome in patients with closed traumatic
brain injury (TBI). It is uncertain whether critical age thresholds exist, however, and the …

The contribution of sleep to hippocampus-dependent memory consolidation

L Marshall, J Born - Trends in cognitive sciences, 2007 - cell.com
There is now compelling evidence that sleep promotes the long-term consolidation of
declarative and procedural memories. Behavioral studies suggest that sleep preferentially …

A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury: results of the Second National Acute Spinal Cord Injury …

MB Bracken, MJ Shepard, WF Collins… - … England Journal of …, 1990 - Mass Medical Soc
Studies in animals indicate that methylprednisolone and naloxone are both potentially
beneficial in acute spinal-cord injury, but whether any treatment is clinically effective remains …

Mammalian evolution and the great American interchange

LG Marshall, SD Webb, JJ Sepkoski Jr, DM Raup - Science, 1982 - science.org
A reciprocal and apparently symmetrical interchange of land mammals between North and
South America began about 3 million years ago, after the appearance of the Panamanian …

Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury: results of the third national acute …

MB Bracken, MJ Shepard, TR Holford, L Leo-Summers… - Jama, 1997 - jamanetwork.com
Objective.—To compare the efficacy of methylprednisolone administered for 24 hours with
methyprednisolone administered for 48 hours or tirilazad mesylate administered for 48 …

The role of secondary brain injury in determining outcome from severe head injury

RM Chesnut, LF Marshall, MR Klauber… - 50 Landmark …, 2019 - api.taylorfrancis.com
As triage and resuscitation protocols evolve, it is critical to determine the major extracranial
variables influencing outcome in the setting of severe head injury. We prospectively studied …

A new classification of head injury based on computerized tomography

LF Marshall, SB Marshall, MR Klauber… - Journal of …, 1991 - thejns.org
✓ A new classification of head injury based primarily on information gleaned from the initial
computerized tomography (CT) scan is described. It utilizes the status of the mesencephalic …

Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data: results of the second National Acute Spinal Cord Injury Study

MB Bracken, MJ Shepard, WF Collins, TR Holford… - Journal of …, 1992 - thejns.org
✓ The 1-year follow-up data of a multicenter randomized controlled trial of
methylprednisolone (30 mg/kg bolus and 5.4 mg/kg/hr for 23 hours) or naloxone (5.4 mg/kg …

Variation in the incidence of uterine leiomyoma among premenopausal women by age and race

LM Marshall, D Spiegelman, RL Barbieri… - Obstetrics & …, 1997 - journals.lww.com
Objective: To quantify the incidence of uterine leiomyoma confirmed by hysterectomy,
ultrasound, or pelvic examination according to age and race among premenopausal …