User profiles for "author:Locker JK"

Jacomina Krijnse Locker

Professor virologie, Giessen university
Verified email at pei.de
Cited by 13812

Cytoplasmic organization of POXvirus DNA replication

B Schramm, JK Locker - Traffic, 2005 - Wiley Online Library
Poxviruses, a family of large DNA viruses, are unique among DNA viruses, because they
carry out DNA replication in the cytoplasm rather than the nucleus. This process does not …

Coronavirus M proteins accumulate in the Golgi complex beyond the site of virion budding

J Klumperman, JK Locker, A Meijer… - Journal of …, 1994 - journals.asm.org
The prevailing hypothesis is that the intracellular site of budding of coronaviruses is
determined by the localization of its membrane protein M (previously called E1). We tested …

Vaccinia virus DNA replication occurs in endoplasmic reticulum-enclosed cytoplasmic mini-nuclei

N Tolonen, L Doglio, S Schleich… - Molecular biology of the …, 2001 - molbiolcell.org
Vaccinia virus (vv), a member of the poxvirus family, is unique among most DNA viruses in
that its replication occurs in the cytoplasm of the infected host cell. Although this viral …

Entry of the two infectious forms of vaccinia virus at the plasma membane is signaling-dependent for the IMV but not the EEV

JK Locker, A Kuehn, S Schleich, G Rutter… - Molecular biology of …, 2000 - molbiolcell.org
The simpler of the two infectious forms of vaccinia virus, the intracellular mature virus (IMV)
is known to infect cells less efficiently than the extracellular enveloped virus (EEV), which is …

Characterization of the coronavirus mouse hepatitis virus strain A59 small membrane protein E

MJB Raamsman, JK Locker, A de Hooge… - Journal of …, 2000 - journals.asm.org
The small envelope (E) protein has recently been shown to play an essential role in the
assembly of coronaviruses. Expression studies revealed that for formation of the viral …

Localization of mouse hepatitis virus nonstructural proteins and RNA synthesis indicates a role for late endosomes in viral replication

Y van der Meer, EJ Snijder, JC Dobbe… - Journal of …, 1999 - journals.asm.org
The aim of the present study was to define the site of replication of the coronavirus mouse
hepatitis virus (MHV). Antibodies directed against several proteins derived from the gene 1 …

[HTML][HTML] Membrane assembly of the triple-spanning coronavirus M protein. Individual transmembrane domains show preferred orientation.

JK Locker, JK Rose, MC Horzinek, PJ Rottier - Journal of Biological …, 1992 - Elsevier
The M protein of mouse hepatitis virus strain A59 is a triple-spanning membrane protein
which assembles with an uncleaved internal signal sequence, adopting an NexoCcyt …

ClpV recycles VipA/VipB tubules and prevents non‐productive tubule formation to ensure efficient type VI protein secretion

N Kapitein, G Bönemann, A Pietrosiuk… - Molecular …, 2013 - Wiley Online Library
The multicomponent type VI secretion system (T6SS) mediates the transport of effector
proteins by puncturing target membranes. T6SSs are suggested to form a contractile …

An unconventional role for cytoplasmic disulfide bonds in vaccinia virus proteins

JK Locker, G Griffiths - The Journal of cell biology, 1999 - rupress.org
Previous data have shown that reducing agents disrupt the structure of vaccinia virus (vv).
Here, we have analyzed the disulfide bonding of vv proteins in detail. In vv-infected cells …

Oligomerization of a trans-Golgi/trans-Golgi network retained protein occurs in the Golgi complex and may be part of its retention

JK Locker, DJE Opstelten, M Ericsson… - Journal of Biological …, 1995 - jbc.org
The mouse hepatitis virus M protein is a triple spanning membrane glycoprotein that, when
expressed independently, localizes to trans-Golgi as well as to the trans-Golgi network …