The striated muscle sarcomere contains the third filament comprising the giant elastic
protein titin, in addition to thick and thin filaments. Titin is the primary source of …

Gut commensal microbes shape the mucosal immune system by regulating the
differentiation and expansion of several types of T cell,,,,. Clostridia, a dominant class of …

Abstract Background In the six Southeast Asian countries that make up the Greater Mekong
Subregion, Plasmodium falciparum has developed resistance to derivatives of artemisinin …

Colorectal cancer (CRC) is a significant cause of cancer-related morbidity and mortality all
over the world. Improvements of cytotoxic and biologic agents have prolonged the survival in …

The heart has an intrinsic ability to increase systolic force in response to a rise in ventricular
filling (the Frank–Starling law of the heart). It is widely accepted that the length dependence …

Genetic robustness, or the ability of an organism to maintain fitness in the presence of
harmful mutations, can be achieved via protein feedback loops. Previous work has …

The resistance of parathyroid cells to 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) in uremic
hyperparathyroidism is thought to be caused, in part, by a 1, 25 (OH) 2D3 receptor (VDR) …

Atomic nuclei are finite quantum systems composed of two distinct types of fermion—protons
and neutrons. In a manner similar to that of electrons orbiting in an atom, protons and …

Conventional assessment of left ventricular (LV) relaxation by calculating the time constant
of LV pressure decay during the isovolumic diastole requires an invasive approach …

An exclusive measurement has been made of the Coulomb dissociation of the two-neutron
halo nucleus Li 11 at 70 MeV/nucleon at RIKEN. Strong low-energy (soft) E 1 excitation is …