Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …

Numerous miRNAs are deregulated in human cancers, and experimental evidence
indicates that they can play roles as oncogenes or tumor suppressor genes. Similarly to …

Molecular diagnostics in cancer should provide the highest specificity and sensitivity in
classification, prognostic stratification and early detection. miRNAs could contribute to hitting …

MicroRNAs (miRNAs) are a class of small noncoding RNAs that control gene expression by
targeting mRNAs and triggering either translation repression or RNA degradation. Their …

Chronic lymphocytic leukemia (CLL) is the most common human leukemia and is
characterized by predominantly nondividing malignant B cells overexpressing the …

Small noncoding microRNAs (miRNAs) can contribute to cancer development and
progression and are differentially expressed in normal tissues and cancers. From a large …

Background MicroRNA expression profiles can be used to distinguish normal B cells from
malignant B cells in patients with chronic lymphocytic leukemia (CLL). We investigated …

Little is known about the expression levels or function of micro-RNAs (miRNAs) in normal
and neoplastic cells, although it is becoming clear that miRNAs play important roles in the …

MicroRNAs (miRNAs) are short non-coding RNA molecules playing regulatory roles in
animals and plants by repressing translation or cleaving RNA transcripts. The specific …

Recent research has identified critical roles for microRNAs in a large number of cellular
processes, including tumorigenic transformation. While significant progress has been made …