Extracting neuronal spiking activity from large-scale two-photon recordings remains
challenging, especially in mammals in vivo, where large noises often contaminate the …

Detecting rapid, coincident changes across sensory modalities is essential for recognition of
sudden threats or events. Using two-photon calcium imaging in identified cell types in …

In recent years, two-photon calcium imaging has become a standard tool to probe the
function of neural circuits and to study computations in neuronal populations. However, the …

Sound recognition relies not only on spectral cues, but also on temporal cues, as
demonstrated by the profound impact of time reversals on perception of common sounds. To …

Olfactory perception and behaviors critically depend on the ability to identify an odor across
a wide range of concentrations. Here, we use calcium imaging to determine how odor …

Twenty years ago, the seminal work of Grinvald et al. revolutionized the view cast on
spontaneous cortical activity by showing how, instead of being a mere measure of noise, it …

There is an increasing interest in using physiologically plausible models in fMRI analysis.
These models do raise new mathematical problems in terms of parameter estimation and …

We survey the recent activities of the Odyssée Laboratory in the area of the application of
mathematics to the design of models for studying brain anatomy and function. We start with …

Across sensory systems, complex spatio-temporal patterns of neural activity arise following
the onset (ON) and offset (OFF) of stimuli. While ON responses have been widely studied …

Spontaneous internal activity plays a major role in higher brain functions. The question of
how it modulates sensory evoked activity and behavior has been explored in anesthetized …