User profiles for "author:Chiossone L"

Laura Chiossone

Innate Pharma Research Laboratories
Verified email at innate-pharma.fr
Cited by 4369

Natural killer cells and other innate lymphoid cells in cancer

L Chiossone, PY Dumas, M Vienne… - Nature Reviews …, 2018 - nature.com
Immuno-oncology is an emerging field that has revolutionized cancer treatment. Most
immunomodulatory strategies focus on enhancing T cell responses, but there has been a …

Tumor-infiltrating natural killer cells

B Cózar, M Greppi, S Carpentier… - Cancer …, 2021 - aacrjournals.org
Because of their potent antitumor activity and their proinflammatory role, natural killer (NK)
cells are at the forefront of efforts to develop immuno-oncologic treatments. NK cells …

Maturation of mouse NK cells is a 4-stage developmental program

L Chiossone, J Chaix, N Fuseri, C Roth… - Blood, The Journal …, 2009 - ashpublications.org
Surface density of CD27 and CD11b subdivides mouse natural killer (NK) cells into 4
subsets: CD11blowCD27low, CD11blowCD27high, CD11bhighCD27high, and …

Natural killer cell immunotherapies against cancer: checkpoint inhibitors and more

L Chiossone, M Vienne, YM Kerdiles, E Vivier - Seminars in immunology, 2017 - Elsevier
After many years of research, recent advances have shed new light on the role of the
immune system in advanced-stage cancer. Various types of immune cells may be useful for …

Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor

T Walzer, L Chiossone, J Chaix, A Calver… - Nature …, 2007 - nature.com
Consistent with their function in immune surveillance, natural killer (NK) cells are distributed
throughout lymphoid and nonlymphoid tissues. However, the mechanisms governing the …

Mesenchymal stromal cells induce peculiar alternatively activated macrophages capable of dampening both innate and adaptive immune responses

L Chiossone, R Conte, GM Spaggiari, M Serra… - Stem Cells, 2016 - academic.oup.com
Mesenchymal stromal cells (MSCs) support hematopoiesis and exert immunoregulatory
activities. Here, we analyzed the functional outcome of the interactions between MSCs and …

Dendritic cell editing by activated natural killer cells results in a more protective cancer-specific immune response

B Morandi, L Mortara, L Chiossone, RS Accolla… - PloS one, 2012 - journals.plos.org
Over the last decade, several studies have extensively reported that activated natural killer
(NK) cells can kill autologous immature dendritic cells (DCs) in vitro, whereas they spare …

Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T‐and NK‐cell proliferation and function

H Abdelrazik, GM Spaggiari… - European journal of …, 2011 - Wiley Online Library
The use of fetal bovine serum (FBS) for the culture and expansion of mesenchymal stromal
cells (MSCs) limits their possible clinical applications. Although some recent studies …

Unique Eomes+ NK Cell Subsets Are Present in Uterus and Decidua During Early Pregnancy

E Montaldo, P Vacca, L Chiossone, D Croxatto… - Frontiers in …, 2016 - frontiersin.org
Decidual and uterine natural killer (NK) cells have been shown to contribute to the
successful pregnancy both in humans and mice. NK cells represent “cytotoxic” group 1 …

Molecular definition of group 1 innate lymphoid cells in the mouse uterus

I Filipovic, L Chiossone, P Vacca, RS Hamilton… - Nature …, 2018 - nature.com
Determining the function of uterine lymphocytes is challenging because of the dynamic
changes in response to sex hormones and, during pregnancy, to the invading foetal …