PhosphoINOSitide-3 Kinase Inhibition In Th17-Dominant Allergic Airway Disease In Mice

ML Manni, ME Clay, KJ McHugh, M Salmon… - C31 …, 2016 - atsjournals.org
hypersecretion, and airway hyperresponsiveness (AHR). Th17 cells, which mediate
neutrophil recruitment, are thought to play a role in asthma pathogenesis, especially those …

C31 EXPERIMENTAL ASTHMA THERAPIES: PhosphoINOSitide-3 Kinase Inhibition In Th17-Dominant Allergic Airway Disease In Mice

ML Manni, ME Clay, KJ McHugh… - American Journal of …, 2016 - search.proquest.com
METHODS: BALB/c SCID mice were treated with OVA (50 µg/mouse) via oropharyngeal
aspiration on Day 0. On Day 1, 1x106 differentiated Th17 cells were adoptively transferred …