Approximately 60%‐80% of patients with primary sclerosing cholangitis (PSC) have
concurrent ulcerative colitis (UC). Previous genome‐wide association studies (GWAS) in …

Pancreatic adenocarcinoma is one of the most aggressive human cancers. It displays many
different chromosomal abnormalities and mutations. By using 244 K high‐resolution array …

Wnt/β‐catenin signaling plays a crucial role in the regulation of colon tissue regeneration
and the development of colon tumors. Under physiological conditions, β‐catenin activity is …

Simple Summary Despite the therapeutic advances, lung cancer is the most dangerous
cancer with poor 5-year survival rate due to metastasis and recurrence. Accumulated …

Cachexia, which is characterised by the wasting of fat and skeletal muscles, is the most
common risk factor for increased mortality rates among patients with advanced lung cancer …

The TCF4 gene encodes for the basic helix–loop–helix transcription factor 4 (TCF4), which
plays an important role in the development of the central nervous system (CNS) …

Colorectal carcinomas (CRC) harbor well-defined genetic abnormalities, including aberrant
activation of β-catenin (β-cat) and KRAS, but independent targeting of these molecules …

Colon cancer stem cells (CCSCs) stand for a critical subpopulation of colon cancer cells that
possess self‐renewal and multilineage differentiation potentials and drive tumorigenicity …

Dysregulation of β-catenin levels and localization and constitutive activation of β-
catenin/TCF (T cell factor)-regulated gene expression occur in many cancers, including the …

Imprinted genes play a critical role in brain development and mental health, although the
underlying molecular and cellular mechanisms remain incompletely understood. The family …