The story of SV40-induced tumorigenesis and cellular transformation is intimately entwined
with the development of modern molecular biology. Because SV40 and other viruses have …

Renaturation kinetics of labeled Agrobacterium tumefaciens DNA are not influenced by
addition of 104-fold excess of crown gall tumor DNA. Reconstruction experiments …

Translocatable elements are stretches of DNA which, as discrete genetic and physical
entities, can move from one position in a procaryotic genome to another position in the same …

Publisher Summary This chapter describes polyacrylamide gel electrophoresis of viral
proteins. Viral structural and nonstructural proteins are agents of expression for the …

GENETICS: SAMBROOK ET AL. alcohol mixture until no protein could be observed at the
interphase, followed by dialysis against SSC/100 containing 0.001 M EDTA. Chromosomes …

High molecular weight DNA, isolated from eleven cloned lines of rat cells independently
transformed by SV40, was cleaved with various restriction endonucleases. The DNA was …

A hypothesis on the structural organization of the operon in the cells of higher organisms is
described. It is assumed that the operon in higher organisms consists of two main parts …

The advent of recombinant DNA technology in the 1970s was a key moment in the history of
both biotechnology and the commercialization of academic research. Doogab Yi's The …

A line of polyoma-transformed mouse cells has been isolated which is fully susceptible to
lytic infection by polyoma virus. This line has been used to select virus mutants which have …

Near the end of the 19th century, the Netherlands scientist, Martinus W. Beijerinck,
performed some experiments which were to have far-reaching consequences in science …