Q fever immunology: the quest for a safe and effective vaccine

G Sam, J Stenos, SR Graves, BHA Rehm - npj Vaccines, 2023 - nature.com
Q fever is an infectious zoonotic disease, caused by the Gram-negative bacterium Coxiella
burnetii. Transmission occurs from livestock to humans through inhalation of a survival form …

FcγRs and their relevance for the activity of anti-CD40 antibodies

I Lang, O Zaitseva, H Wajant - International Journal of Molecular Sciences, 2022 - mdpi.com
Simple Summary Targeting of CD40 with antibodies attracts significant translational interest.
While inhibitory CD40 targeting appears particularly attractive in the field of organ …

[HTML][HTML] Bidirectional and persistent immunomodulation of Astragalus polysaccharide as an adjuvant of influenza and recombinant SARS-CoV-2 vaccine

D Zhao, X Chen, L Wang, J Zhang, Z Zhao… - International Journal of …, 2023 - Elsevier
Respiratory viral infections, such as coronavirus disease of 2019 (COVID-19) and influenza,
cause significant morbidity and mortality and have become a worldwide public health …

Lycium barbarum polysaccharides-loaded Particulate Alum via Pickering emulsion as an adjuvant to enhance immune responses

Z Fan, Y Zhang, L Jiao, T Zhu, Z Feng, Z Liu… - International Journal of …, 2023 - Elsevier
Pickering emulsion has great potential as a vaccine adjuvant due to its unique advantages
such as its high antigen loading efficiency, great stability, etc. Among several adjuvants on …

Double-layered N-S1 protein nanoparticle immunization elicits robust cellular immune and broad antibody responses against SARS-CoV-2

R Li, Z Chang, H Liu, Y Wang, M Li, Y Chen… - Journal of …, 2024 - Springer
Background The COVID-19 pandemic is a persistent global threat to public health. As for the
emerging variants of SARS-CoV-2, it is necessary to develop vaccines that can induce …

[HTML][HTML] Soluble CD40 Ligand as a Promising Biomarker in Cancer Diagnosis

A Pazoki, S Dadfar, A Shadab, D Haghmorad… - Cells, 2024 - mdpi.com
Cancer remains a significant challenge in medicine due to its complexity and heterogeneity.
Biomarkers have emerged as vital tools for cancer research and clinical practice, facilitating …

CAR T-cell therapy for systemic lupus erythematosus: current status and future perspectives

J Zhou, B Lei, F Shi, X Luo, K Wu, Y Xu… - Frontiers in …, 2024 - frontiersin.org
Systemic lupus erythematosus (SLE) and lupus nephritis (LN) are debilitating autoimmune
disorders characterized by pathological autoantibodies production and immune dysfunction …

Cell targeting and immunostimulatory properties of a novel Fcγ-receptor-independent agonistic anti-CD40 antibody in rhesus macaques

X Yan, S Ols, R Arcoverde Cerveira, K Lenart… - Cellular and Molecular …, 2023 - Springer
Targeting CD40 by agonistic antibodies used as vaccine adjuvants or for cancer
immunotherapy is a strategy to stimulate immune responses. The majority of studied …

Tertiary lymphoid structures are associated with enhanced macrophage and dendritic cell activation and proximity to CD8+ T cells, which better predict the clinical …

L Gorvel, M Panouillot, MS Rouvière, J Sonongbua… - bioRxiv, 2023 - biorxiv.org
Cervical tumors are usually treated using surgery, chemotherapy, and radiotherapy, and
would benefit from immunotherapies. However, the immune microenvironment in cervical …

Combining anti-checkpoint immunotherapies and cancer vaccines as a novel strategy in oncological therapy: A review

H Ghaneialvar, S Jahani, E Hashemi, MA Khalilzad… - Human Immunology, 2025 - Elsevier
The field of cancer immunotherapy has experienced remarkable advancements in the
treatment of human cancers over recent decades. Therapeutic cancer vaccines have been …