The PCR, like recombinant DNA technology, has had an enormous impact in both basic and
diagnostic aspects of molecular biology because it can produce large amounts of a specific …

Whole genome amplification methods are used to generate the large amounts of DNA that
are required for genetic testing. Preparation of genomic DNA from clinical samples is a …

A new procedure has been developed for the efficient cloning of complex PCR mixtures,
resulting in libraries exclusively consisting of recombinant clones. Recombinants are …

A version of the polymerase chain reaction (PCR), termed degenerate oligonucleotide-
primed PCR (DOP-PCR), which employs oligonucleotides of partially degenerate sequence …

The heterogeneity of neural gene expression and the spatially limited expression of many
low-abundance messenger RNAs in the brain has made cloning and analysis of such …

We have developed an in vitro method for amplifying a large fraction of the DNA sequences
present in a single haploid cell by repeated primer extensions using a mixture of 15-base …

The present invention regards a variety of methods and compositions for whole genome
amplification. In a particular aspect of the present invention, there is a method of amplifying a …

Genetic analysis of limiting quantities of genomic DNA play an important role in DNA
forensics, paleoarcheology, genetic disease diagnosis, genetic linkage analysis, and …

Structural genetic alterations in cancer often involve gene loss or gene amplification. With
the advent of microarray approaches for the analysis of the genome, as exemplified by array …

The polymerase chain reaction (PCR) is a powerful new method for 'in vitro cloning'. It can
selectively amplify a single molecule of template DNA several millionfold in a few hours and …