Lasers with pulse lengths from nanoseconds to femtoseconds and wavelengths from the mid-
infrared to extreme ultraviolet (UV) have been used for desorption or ablation in mass …

Lasers have long been used in the field of mass spectrometric analysis for characterization
of condensed matter. However, emission of neutrals upon laser irradiation surpasses the …

Mass spectrometry imaging (MSI) technologies are widely used today to study the in situ
spatial distributions for a variety of analytes. As these technologies advance, the pursuit of …

Ultrashort pulses from femtosecond (fs) lasers can be used to ablate any material regardless
of the target's optical properties. Another important aspect of fs laser pulses is that, while …

Rationale Traditionally, drug analysis in biological tissue by mass spectrometry has required
complicated sample pre‐treatment, which not only wasted time, but also had adverse effects …

Vacuum ultraviolet (VUV) single photon ionization mass spectrometry (SPI-MS) is a vacuum-
based technique typically used for the analysis of gas phase and solid samples, but not for …

Localization and quantification of the target drug in tissues is a key indicator of efficacy in
drug discovery. In contrast to established methods that require matrices and complex …

A novel pretreatment-free method involving laser desorption postionization (LDPI) coupled
with time-of-flight mass spectrometry (MS) was developed for the monitoring of proflavine …

Wide and abusive applications of fungicides (such as chlorothalonil) in agricultural
production have caused various adverse effects on the environment, especially on soil …

Oxygenated polycyclic aromatic hydrocarbons (OPAHs) are mutagenic and ubiquitous
pollutants to both humans and environment. Routine analytical methods for differentiating …