The mechanisms of CD95 (Fas/APO-1)-mediated extrinsic apoptotic pathway in cancer cells
have been extensively studied. The majority of human cells express CD95, but not all these …

Programmed cell death represents a precisely regulated and active cellular demise,
governed by a complex network of specific genes and proteins. The identification of multiple …

Despite enormous efforts being invested in the development of novel therapies for brain
malignancies, there remains a dire need for effective treatments, particularly for pediatric …

Glioblastoma multiforme (GBM) is a malignant tumor of the brain that is considered to be
incurable. Currently, surgical removal of tumors, chemotherapy with temozolomide, and …

CAR T cell therapy has revolutionized how we deliver cancer treatment, most notably for
hematologic cancers, by compelling T cells to recognize and kill tumor cells. Nevertheless …

Tumor-associated macrophage (TAM) affects the intrinsic properties of tumor cells and the
tumor microenvironment (TME), which can stimulate tumor cell proliferation, migration, and …

In conjunction with research in molecular genetics and cancer biology, development in
analytical tools has fundamentally changed our understanding of cancer. Over the last three …

The regulatory role of autophagy-related genes (ARGs) on the differentiation trajectory and
immune landscape of glioblastoma remained obscure. This research identified 11 ARGs …