Glioblastoma multiforme (GBM) is the most common form of brain cancer and one of the
most aggressive cancers found in humans. Most of the signs and symptoms of GBM can be …

MicroRNAs, the non-coding single-stranded RNA of 19–25 nucleotides are emerging as
robust players of gene regulation. Plethora of evidences support that the ability of …

Epigenetic and metabolic alterations incancer cells are highly associated. Glioblastoma
multiforme (GBM) is a complicated pathological process with dysregulated methylation and …

The evasion of anti-growth signaling is an important characteristic of cancer cells. In order to
continue to proliferate, cancer cells must somehow uncouple themselves from the many …

Pulmonary arterial hypertension (PAH) is a devastating disease without effective treatment.
Despite decades of research and the development of novel treatments, PAH remains a fatal …

Glioblastoma multiforme (GBM) is the most common primary brain malignancy and is often
resistant to conventional treatments due to its extensive cellular heterogeneity. Thus, the …

Osteoclasts are specialized bone-resorbing cells that contribute to physiological bone
development and remodeling in bone metabolism throughout life. Abnormal production and …

Cardiac fibrosis is a major cause of heart failure. Micro RNA s (miRs) are important
epigenetic regulators of cardiac function and cardiovascular diseases, including cardiac …

Once thought of as inert remnants of cellular processes, the significance of membrane
vesicles is now expanding as their capacity to package and transfer bioactive molecules …

Glioblastoma multiforme is the most frequent, aggressive and fatal type of brain tumor.
Glioblastomas are characterized by their infiltrating nature, high proliferation rate and …