Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Recent progress of supramolecular chemotherapy based on host–guest interactions
M Yan, S Wu, Y Wang, M Liang, M Wang… - Advanced …, 2024 - Wiley Online Library
Chemotherapy is widely recognized as an effective approach for treating cancer due to its
ability to eliminate cancer cells using chemotherapeutic drugs. However, traditional …
ability to eliminate cancer cells using chemotherapeutic drugs. However, traditional …
A host–guest strategy for converting the photodynamic agents from a singlet oxygen generator to a superoxide radical generator
Type-I photosensitizers (PSs) generate cytotoxic oxygen radicals by electron transfer even in
a hypoxic environment. Nevertheless, the preparation of type-I PSs remains a challenge due …
a hypoxic environment. Nevertheless, the preparation of type-I PSs remains a challenge due …
Challenges and opportunities of functionalized cucurbiturils for biomedical applications
Cucurbit [n] uril (CB [n]) macrocycles (especially CB [5] to CB [8]) have shown exceptional
attributes since their discovery in 2000. Their stability, water solubility, responsiveness to …
attributes since their discovery in 2000. Their stability, water solubility, responsiveness to …
Strategic design of conquering hypoxia in tumor for advanced photodynamic therapy
C Zhang, X Hu, L Jin, L Lin, H Lin… - Advanced Healthcare …, 2023 - Wiley Online Library
Photodynamic therapy (PDT), with its advantages of high targeting, minimally invasive, and
low toxicity side effects, has been widely used in the clinical therapy of various tumors …
low toxicity side effects, has been widely used in the clinical therapy of various tumors …
Nanomaterials-based photosensitizers and delivery systems for photodynamic cancer therapy
XT Yu, SY Sui, YX He, CH Yu, Q Peng - Biomaterials Advances, 2022 - Elsevier
The increasing cancer morbidity and mortality requires the development of high-efficiency
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …
Current advances in photodynamic therapy (PDT) and the future potential of PDT-combinatorial cancer therapies
Photodynamic therapy (PDT) is a two-stage treatment that implies the use of light energy,
oxygen, and light-activated compounds (photosensitizers) to elicit cancerous and …
oxygen, and light-activated compounds (photosensitizers) to elicit cancerous and …
Recent progress of metal-organic framework-based photodynamic therapy for cancer treatment
Y Ye, Y Zhao, Y Sun, J Cao - International Journal of …, 2022 - Taylor & Francis
Photodynamic therapy (PDT), combining photosensitizers (PSs) and excitation light at a
specific wavelength to produce toxic reactive oxygen species, has been a novel and …
specific wavelength to produce toxic reactive oxygen species, has been a novel and …
CD44-mediated tumor homing of hyaluronic acid nanogels for hypoxia-activated photodynamic therapy against tumor
HY Yang, MS Jang, XS Sun, CL Liu, JH Lee… - Colloids and Surfaces B …, 2023 - Elsevier
In this study, unique hypoxia-activated hyaluronic acid nanogels (HANGs) were reported for
CD44-targeted delivery of photosensitizers (chlorin e6, Ce6) for diagnostic imaging and …
CD44-targeted delivery of photosensitizers (chlorin e6, Ce6) for diagnostic imaging and …
Tumor microenvironment targeting for glioblastoma multiforme treatment via hybrid cell membrane coating supramolecular micelles
Glioblastoma multiforme (GBM) is one of the most common primary intracranial tumors in the
central nervous system with poor prognosis, high invasiveness, risk of recurrence and low …
central nervous system with poor prognosis, high invasiveness, risk of recurrence and low …