Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Recent progress of supramolecular chemotherapy based on host–guest interactions

M Yan, S Wu, Y Wang, M Liang, M Wang… - Advanced …, 2024 - Wiley Online Library
Chemotherapy is widely recognized as an effective approach for treating cancer due to its
ability to eliminate cancer cells using chemotherapeutic drugs. However, traditional …

A host–guest strategy for converting the photodynamic agents from a singlet oxygen generator to a superoxide radical generator

KX Teng, LY Niu, QZ Yang - Chemical Science, 2022 - pubs.rsc.org
Type-I photosensitizers (PSs) generate cytotoxic oxygen radicals by electron transfer even in
a hypoxic environment. Nevertheless, the preparation of type-I PSs remains a challenge due …

Challenges and opportunities of functionalized cucurbiturils for biomedical applications

H Yin, Q Cheng, D Bardelang, R Wang - JACS Au, 2023 - ACS Publications
Cucurbit [n] uril (CB [n]) macrocycles (especially CB [5] to CB [8]) have shown exceptional
attributes since their discovery in 2000. Their stability, water solubility, responsiveness to …

Strategic design of conquering hypoxia in tumor for advanced photodynamic therapy

C Zhang, X Hu, L Jin, L Lin, H Lin… - Advanced Healthcare …, 2023 - Wiley Online Library
Photodynamic therapy (PDT), with its advantages of high targeting, minimally invasive, and
low toxicity side effects, has been widely used in the clinical therapy of various tumors …

Nanomaterials-based photosensitizers and delivery systems for photodynamic cancer therapy

XT Yu, SY Sui, YX He, CH Yu, Q Peng - Biomaterials Advances, 2022 - Elsevier
The increasing cancer morbidity and mortality requires the development of high-efficiency
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …

Current advances in photodynamic therapy (PDT) and the future potential of PDT-combinatorial cancer therapies

N Alvarez, A Sevilla - International Journal of Molecular Sciences, 2024 - mdpi.com
Photodynamic therapy (PDT) is a two-stage treatment that implies the use of light energy,
oxygen, and light-activated compounds (photosensitizers) to elicit cancerous and …

Recent progress of metal-organic framework-based photodynamic therapy for cancer treatment

Y Ye, Y Zhao, Y Sun, J Cao - International Journal of …, 2022 - Taylor & Francis
Photodynamic therapy (PDT), combining photosensitizers (PSs) and excitation light at a
specific wavelength to produce toxic reactive oxygen species, has been a novel and …

CD44-mediated tumor homing of hyaluronic acid nanogels for hypoxia-activated photodynamic therapy against tumor

HY Yang, MS Jang, XS Sun, CL Liu, JH Lee… - Colloids and Surfaces B …, 2023 - Elsevier
In this study, unique hypoxia-activated hyaluronic acid nanogels (HANGs) were reported for
CD44-targeted delivery of photosensitizers (chlorin e6, Ce6) for diagnostic imaging and …

Tumor microenvironment targeting for glioblastoma multiforme treatment via hybrid cell membrane coating supramolecular micelles

X Huang, N Mu, Y Ding, R Huang, W Wu, L Li… - Journal of Controlled …, 2024 - Elsevier
Glioblastoma multiforme (GBM) is one of the most common primary intracranial tumors in the
central nervous system with poor prognosis, high invasiveness, risk of recurrence and low …