Evolution, heterogeneity and global dispersal of cosmopolitan genotype of Dengue virus type 2

SP Yenamandra, C Koo, S Chiang, HSJ Lim, ZY Yeo… - Scientific Reports, 2021 - nature.com
Abstract Dengue virus type 2 (DENV-2) contributes substantially to the dengue burden and
dengue-related mortality in the tropics and sub-tropics. DENV-2 includes six genotypes …

Development of nucleic acid-based vaccines against dengue and other mosquito-borne flaviviruses: the past, present, and future

MB Bello, A Alsaadi, A Naeem, SA Almahboub… - Frontiers in …, 2025 - frontiersin.org
Due to their widespread geographic distribution and frequent outbreaks, mosquito-borne
flaviviruses, such as DENV (DENV), Zika virus (ZIKV), Japanese encephalitis virus (JEV) …

Dengue Virus and Vaccines: How Can DNA Immunization Contribute to This Challenge?

AMB Alves, SM Costa, PBA Pinto - Frontiers in medical technology, 2021 - frontiersin.org
Dengue infections still have a tremendous impact on public health systems in most countries
in tropical and subtropical regions. The disease is systemic and dynamic with broad range of …

Anti-hepatitis C virus activity of a crude extract from longan (Dimocarpus longan Lour.) leaves

DR Apriyanto, C Aoki, S Hartati, M Hanafi… - Japanese journal of …, 2016 - jstage.jst.go.jp
Infection with hepatitis C virus (HCV) results in hepatitis C, a disease characterized by
chronic infection, cirrhosis, and hepatocellular carcinoma. Currently, the standard therapy is …

Divergence of the dengue virus type 2 Cosmopolitan genotype associated with two predominant serotype shifts between 1 and 2 in Surabaya, Indonesia, 2008–2014

T Kotaki, A Yamanaka, KC Mulyatno, S Churrotin… - Infection, Genetics and …, 2016 - Elsevier
Indonesia is one of the biggest dengue endemic countries, and, thus, is an important place
to investigate the evolution of dengue virus (DENV). We have continuously isolated DENV in …

[HTML][HTML] Clinical, Virological, and Immunological Features in Cosmopolitan Genotype DENV-2–Infected Patients during a Large Dengue Outbreak in Sri Lanka in 2017

KM Nwe, MMN Tun, R Muthugala… - … American Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
In 2017, Sri Lanka experienced its largest dengue epidemic and reported severe and
unusual presentations of dengue with high morbidity. This outbreak was associated with the …

Antibody‐dependent enhancement (ADE) of dengue virus: identification of the key amino acid that is vital in denv vaccine research

G Cui, L Si, Y Wang, J Zhou, H Yan… - The journal of gene …, 2021 - Wiley Online Library
Background The antibody‐dependent enhancement (ADE) of dengue virus (DENV) has
critically restricted vaccine development. Prior research suggested pr4 as the probable ADE …

[HTML][HTML] Emergence of a Novel Dengue Virus Serotype-2 Genotype IV Lineage III Strain and Displacement of Dengue Virus Serotype-1 in Central India (2019–2023)

AK Yadav, R Chowdhary, A Siddiqui, AG Malhotra… - Viruses, 2025 - mdpi.com
Dengue fever remains a significant public health concern in tropical regions, including
Central India, where outbreaks are frequent and associated with high morbidity and …

DENV-3 precursor membrane (prM) glycoprotein enhances E protein immunogenicity and confers protection against DENV-2 infections in a murine model

RS Dias, MD Teixeira, MF Xisto… - Human Vaccines & …, 2021 - Taylor & Francis
To improve a DNA vaccine containing the truncated dengue virus serotype 2 (DENV-2)
envelope (E) protein and evaluate the influence of precursor membrane (prM) glycoprotein …

Expression of Recombinant Non Structural 1 Protein of Dengue Virus Serotype-2 in Mammalian Cell Lin

OC MUSTIKA, A Budianti, TM Sudiro - Microbiology Indonesia, 2019 - scholar.ui.ac.id
Dengue infection is a global infectious disease with almost 100 million cases occur annually
in over more than 100 endemic countries. Dengue virus (DENV), the causative agent of …