Introduction: Platelet-rich plasma (PRP) is an autologous blood-derived product that
contains platelet concentrations at least 2/3 times above the normal level and includes …

In the last years, mesenchymal stem cell (MSC)-based therapies have become an
interesting therapeutic opportunity for the treatment of rheumatoid arthritis (RA) due to their …

Mesenchymal stem/stromal cells (MSCs) represent a promising therapy for musculoskeletal
diseases. There is compelling evidence indicating that MSC effects are mainly mediated by …

Background Dental pulp stem cells (DPSCs) are low immunogenic and hold
immunomodulatory properties that, along with their well-established multi-potency, might …

Background Bone marrow mesenchymal stem cells (BM-MSCs) can dampen inflammation
in animal models of inflammatory rheumatisms and human osteoarthritis. They are expected …

Considered for decades as a cartilage disease, recent studies of osteoarthritis (OA) take us
back to the concepts discussed at the naming of the disorder as “bone-joint-inflammation” …

Introduction Mesenchymal stromal cells (MSC) from Wharton's jelly of umbilical cord is
primitive and serve as an inexhaustible source of stem cells with greater potential in clinics …

Rheumatoid arthritis (RA) is a Th1/Th17‐mediated autoimmune disease whose current
treatment, consisting in the blockage of inflammatory cytokines by disease‐modifying …

As the world's population is aging, the incidence of the degenerative disease Osteoarthritis
(OA) is increasing. Current treatment options of OA focus on the alleviation of the symptoms …

The purpose of regenerative medicine is to restore or enhance the normal function of human
cells, tissues, and organs. From a clinical point of view, the use of stem cells is more …