Structural brain changes associated with overweight and obesity

E Gómez-Apo, A Mondragón-Maya… - Journal of …, 2021 - Wiley Online Library
Obesity is a global health problem with a broad set of comorbidities, such as malnutrition,
metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. This …

Gingiva-derived mesenchymal stem cells: potential application in tissue engineering and regenerative medicine-a comprehensive review

D Kim, AE Lee, Q Xu, Q Zhang, AD Le - Frontiers in Immunology, 2021 - frontiersin.org
A unique subpopulation of mesenchymal stem cells (MSCs) has been isolated and
characterized from human gingival tissues (GMSCs). Similar to MSCs derived from other …

Macrophage polarization in atherosclerosis

S Eshghjoo, DM Kim, A Jayaraman, Y Sun, RC Alaniz - Genes, 2022 - mdpi.com
The implication of the heterogeneous spectrum of pro-and anti-inflammatory macrophages
(Macs) has been an important area of investigation over the last decade. The polarization of …

The role of macrophages in the pathogenesis of SARS-CoV-2-associated acute respiratory distress syndrome

A Kosyreva, D Dzhalilova, A Lokhonina… - Frontiers in …, 2021 - frontiersin.org
Macrophages are cells that mediate both innate and adaptive immunity reactions, playing a
major role in both physiological and pathological processes. Systemic SARS-CoV-2 …

Current state of cold atmospheric plasma and cancer‐immunity cycle: therapeutic relevance and overcoming clinical limitations using hydrogels

M Živanić, A Espona‐Noguera, A Lin… - Advanced …, 2023 - Wiley Online Library
Cold atmospheric plasma (CAP) is a partially ionized gas that gains attention as a well‐
tolerated cancer treatment that can enhance anti‐tumor immune responses, which are …

Cell therapy using ex vivo reprogrammed macrophages enhances antitumor immune responses in melanoma

SR Noonepalle, M Gracia-Hernandez… - Journal of Experimental …, 2024 - Springer
Background Macrophage-based cell therapies have shown modest success in clinical trials,
which can be attributed to their phenotypic plasticity, where transplanted macrophages get …

Biomaterial-assisted macrophage cell therapy for regenerative medicine

S Sung, LA Steele, GE Risser, KL Spiller - Advanced drug delivery reviews, 2023 - Elsevier
Although most tissue types are capable of some form of self-repair and regeneration, injuries
that are larger than a critical threshold or those occurring in the setting of certain diseases …

Immunomodulatory activity of manganese dioxide nanoparticles: Promising for novel vaccines and immunotherapeutics

Y Huang, Y Ruan, Y Ma, D Chen, T Zhang… - Frontiers in …, 2023 - frontiersin.org
Manganese (Mn), a nutrient inorganic trace element, is necessary for a variety of
physiological processes of animal body due to their important roles in oxidative regulation …

Mdivi-1 modulates macrophage/microglial polarization in mice with EAE via the inhibition of the TLR2/4-GSK3β-NF-κB inflammatory signaling axis

X Liu, X Zhang, X Niu, P Zhang, Q Wang, X Xue… - Molecular …, 2022 - Springer
Macrophage/microglial modulation plays a critical role in the pathogenesis of multiple
sclerosis (MS), which is an inflammatory disorder of the central nervous system. Dynamin …

Nanocarriers for effective delivery: modulation of innate immunity for the management of infections and the associated complications

CN Ko, S Zang, Y Zhou, Z Zhong, C Yang - Journal of nanobiotechnology, 2022 - Springer
Innate immunity is the first line of defense against invading pathogens. Innate immune cells
can recognize invading pathogens through recognizing pathogen-associated molecular …