Annually increasing incidence of cardiac-related disorders and cardiac tissue's minimal
regenerative capacity have motivated the researchers to explore effective therapeutic …

Myocardial infarction is the most significant manifestation of ischemic heart disease and is
associated with high morbidity and mortality. Novel strategies targeting at regenerating the …

Background Bone marrow mesenchymal stem cells (MSCs) are among the most common
cell types to be used and studied for cardiac regeneration. Low survival rate and difficult …

Background Exosomes derived from mesenchymal stem cells (MSC s) were proved to boost
cell proliferation and angiogenic potency. We explored whether cardiac stem cells (CSCs) …

Cardiac stem cells (CSCs) have emerged as one of the most promising stem cells for
cardiac protection. Recently, exosomes from bone marrow‐derived mesenchymal stem cells …

Stem cell (SC) therapy for ischemic cardiomyopathy is hampered by poor survival of the
implanted cells. Recently, SC-derived exosomes have been shown to facilitate cell …

Autophagy is a highly conserved cellular process that degrades modified, surplus, or
harmful cytoplasmic components by sequestering them in autophagosomes which then …

With multipotent differentiation potential and paracrine capacity, mesenchymal stem cells
(MSCs) have been widely applied in clinical practice for the treatment of ischemic heart …

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Introduction: Over the past decade, it has become clear that long-term engraftment of any ex
vivo expanded cell product transplanted into injured myocardium is modest and all …