| The continuum of spreading depolarizations in acute cortical lesion development: examining Leao’s legacy JA Hartings, CW Shuttleworth, SA Kirov, C Ayata, JM Hinzman, ... Journal of Cerebral Blood Flow & Metabolism 37 (5), 1571-1594, 2017 | 410 | 2017 |
| Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: review and recommendations of the COSBID research group JP Dreier, M Fabricius, C Ayata, OW Sakowitz, C William Shuttleworth, ... Journal of Cerebral Blood Flow & Metabolism 37 (5), 1595-1625, 2017 | 351 | 2017 |
| Co-localization of nitric oxide synthase immunoreactivity and NADPH diaphorase staining in neurons of the guinea-pig intestine HM Young, JB Furness, CWR Shuttleworth, DS Bredt, SH Snyder Histochemistry 97 (4), 375-378, 1992 | 331 | 1992 |
| NADPH diaphorase and nitric oxide synthase colocalization in enteric neurons of canine proximal colon SM Ward, C Xue, CW Shuttleworth, DS Bredt, SH Snyder, KM Sanders American Journal of Physiology-Gastrointestinal and Liver Physiology 263 (2 …, 1992 | 227 | 1992 |
| Zinc: new clues to diverse roles in brain ischemia CW Shuttleworth, JH Weiss Trends in pharmacological sciences 32 (8), 480-486, 2011 | 203 | 2011 |
| Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen–glucose deprivation model of ischemia YV Medvedeva, B Lin, CW Shuttleworth, JH Weiss Journal of Neuroscience 29 (4), 1105-1114, 2009 | 203 | 2009 |
| NAD (P) H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices CW Shuttleworth, AM Brennan, JA Connor Journal of Neuroscience 23 (8), 3196-3208, 2003 | 178 | 2003 |
| Spreading depolarization in acute brain injury inhibited by ketamine: a prospective, randomized, multiple crossover trial AP Carlson, M Abbas, RL Alunday, F Qeadan, CW Shuttleworth Journal of neurosurgery 130 (5), 1513-1519, 2018 | 168 | 2018 |
| Nimodipine reappraised: an old drug with a future AP Carlson, D Hänggi, RL Macdonald, CW Shuttleworth Current neuropharmacology 18 (1), 65-82, 2020 | 146 | 2020 |
| Immunohistochemical localization of 3', 5'-cyclic guanosine monophosphate in the canine proximal colon: responses to nitric oxide and electrical stimulation of enteric … CW Shuttleworth, C Xue, SM Ward, J De Vente, KM Sanders Neuroscience 56 (2), 513-522, 1993 | 142 | 1993 |
| Zn2+ influx is critical for some forms of spreading depression in brain slices RM Dietz, JH Weiss, CW Shuttleworth Journal of Neuroscience 28 (32), 8014-8024, 2008 | 127 | 2008 |
| NAD (P) H fluorescence transients after synaptic activity in brain slices: predominant role of mitochondrial function AM Brennan, JA Connor, CW Shuttleworth Journal of Cerebral Blood Flow & Metabolism 26 (11), 1389-1406, 2006 | 114 | 2006 |
| Use of NAD (P) H and flavoprotein autofluorescence transients to probe neuron and astrocyte responses to synaptic activation CW Shuttleworth Neurochemistry international 56 (3), 379-386, 2010 | 111 | 2010 |
| Neural stem/progenitor cells display a low requirement for oxidative metabolism independent of hypoxia inducible factor‐1alpha expression KM Candelario, CW Shuttleworth, LA Cunningham Journal of neurochemistry 125 (3), 420-429, 2013 | 109 | 2013 |
| Evidence that nitric oxide participates in non-adrenergic inhibitory transmission to intestinal muscle in the guinea-pig CWR Shuttleworth, R Murphy, JB Furness Neuroscience letters 130 (1), 77-80, 1991 | 101 | 1991 |
| The critical role of spreading depolarizations in early brain injury: consensus and contention RD Andrew, JA Hartings, C Ayata, KC Brennan, KD Dawson-Scully, ... Neurocritical care 37 (Suppl 1), 83-101, 2022 | 98 | 2022 |
| Relationship between nitric oxide and vasoactive intestinal polypeptide in enteric inhibitory neurotransmission KD Keef, CWR Shuttleworth, C Xue, O Bayguinov, NG Publicover, ... Neuropharmacology 33 (11), 1303-1314, 1994 | 88 | 1994 |
| Direct visualization of trapped erythrocytes in rat brain after focal ischemia and reperfusion S Liu, J Connor, S Peterson, CW Shuttleworth, KJ Liu Journal of Cerebral Blood Flow & Metabolism 22 (10), 1222-1230, 2002 | 85 | 2002 |
| Light-and electron-microscopic immunochemical analysis of nerve fibre types innervating the taenia of the guinea-pig caecum JB Furness, S Pompolo, CWR Shuttleworth, DE Burleigh Cell and tissue research 270 (1), 125-137, 1992 | 85 | 1992 |
| Sustained NMDA receptor activation by spreading depolarizations can initiate excitotoxic injury in metabolically compromised neurons I Aiba, CW Shuttleworth The Journal of physiology 590 (22), 5877-5893, 2012 | 84 | 2012 |
