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Adrian Israelson
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Potential roles of gut microbiome and metabolites in modulating ALS in mice
E Blacher, S Bashiardes, H Shapiro, D Rothschild, U Mor, ...
Nature 572 (7770), 474-480, 2019
5862019
In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death
H Azoulay-Zohar, A Israelson, S Abu-Hamad, V Shoshan-Barmatz
Biochemical Journal 377 (2), 347-355, 2004
4892004
The voltage-dependent anion channel (VDAC): function in intracellular signalling, cell life and cell death
V Shoshan-Barmatz, A Israelson, D Brdiczka, SS Sheu
Current pharmaceutical design 12 (18), 2249-2270, 2006
4042006
Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS
A Israelson, N Arbel, S Da Cruz, H Ilieva, K Yamanaka, ...
Neuron 67 (4), 575-587, 2010
3502010
The voltage-dependent anion channel-1 modulates apoptotic cell death
H Zaid, S Abu-Hamad, A Israelson, I Nathan, V Shoshan-Barmatz
Cell Death & Differentiation 12 (7), 751-760, 2005
3452005
Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: mapping the site of binding
S Abu-Hamad, H Zaid, A Israelson, E Nahon, V Shoshan-Barmatz
Journal of Biological Chemistry 283 (19), 13482-13490, 2008
3002008
The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins
S Abu-Hamad, N Arbel, D Calo, L Arzoine, A Israelson, N Keinan, ...
Journal of cell science 122 (11), 1906-1916, 2009
2772009
Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria
R Zalk, A Israelson, ES Garty, H Azoulay-Zohar, V Shoshan-Barmatz
Biochemical Journal 386 (1), 73-83, 2005
2572005
Methyl jasmonate binds to and detaches mitochondria-bound hexokinase
N Goldin, L Arzoine, A Heyfets, A Israelson, Z Zaslavsky, T Bravman, ...
Oncogene 27 (34), 4636-4643, 2008
2352008
ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import
Q Li, C Vande Velde, A Israelson, J Xie, AO Bailey, MQ Dong, SJ Chun, ...
Proceedings of the National Academy of Sciences 107 (49), 21146-21151, 2010
1902010
Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1
A Israelson, D Ditsworth, S Sun, SW Song, J Liang, M Hruska-Plochan, ...
Neuron 86 (1), 218-232, 2015
1272015
Fluoxetine (Prozac) interaction with the mitochondrial voltage-dependent anion channel and protection against apoptotic cell death
E Nahon, A Israelson, S Abu-Hamad, V Shoshan-Barmatz
FEBS letters 579 (22), 5105-5110, 2005
1142005
The voltage-dependent anion channel in endoplasmic/sarcoplasmic reticulum: characterization, modulation and possible function
V Shoshan-Barmatz, A Israelson
The Journal of membrane biology 204, 57-66, 2005
932005
Macrophage migration inhibitory factor: a multifaceted cytokine implicated in multiple neurological diseases
MF Leyton-Jaimes, J Kahn, A Israelson
Experimental neurology 301, 83-91, 2018
892018
Localization of the voltage-dependent anion channel-1 Ca2+-binding sites
A Israelson, S Abu-Hamad, H Zaid, E Nahon, V Shoshan-Barmatz
Cell Calcium 41 (3), 235-244, 2007
782007
MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS
N Shvil, V Banerjee, G Zoltsman, T Shani, J Kahn, S Abu-Hamad, N Papo, ...
Cell death & disease 9 (2), 107, 2018
682018
Mapping the ruthenium red-binding site of the voltage-dependent anion channel-1
A Israelson, H Zaid, S Abu-Hamad, E Nahon, V Shoshan-Barmatz
Cell calcium 43 (2), 196-204, 2008
612008
Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS
MF Leyton-Jaimes, C Benaim, S Abu-Hamad, J Kahn, A Guetta, R Bucala, ...
Proceedings of the National Academy of Sciences 113 (36), 10198-10203, 2016
492016
Cu/Zn-superoxide dismutase and wild-type like fALS SOD1 mutants produce cytotoxic quantities of H2O2 via cysteine-dependent redox short-circuit
S Bakavayev, N Chetrit, T Zvagelsky, R Mansour, M Vyazmensky, Z Barak, ...
Scientific reports 9 (1), 10826, 2019
422019
AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS
MF Leyton-Jaimes, J Kahn, A Israelson
Proceedings of the National Academy of Sciences 116 (29), 14755-14760, 2019
422019
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