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Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance.
Choi CS, Savage DB, Kulkarni A, Yu XX, Liu ZX, Morino K, Kim S, Distefano A, Samuel VT, Neschen S, Zhang D, Wang A, Zhang XM, Kahn M, Cline GW, Pandey SK, Geisler JG, Bhanot S, Monia BP, Shulman GI. Choi CS, et al. Among authors: samuel vt. J Biol Chem. 2007 Aug 3;282(31):22678-88. doi: 10.1074/jbc.M704213200. Epub 2007 May 27. J Biol Chem. 2007. PMID: 17526931 Free article.
Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism.
Choi CS, Befroy DE, Codella R, Kim S, Reznick RM, Hwang YJ, Liu ZX, Lee HY, Distefano A, Samuel VT, Zhang D, Cline GW, Handschin C, Lin J, Petersen KF, Spiegelman BM, Shulman GI. Choi CS, et al. Among authors: samuel vt. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19926-31. doi: 10.1073/pnas.0810339105. Epub 2008 Dec 9. Proc Natl Acad Sci U S A. 2008. PMID: 19066218 Free PMC article.
108 results