Murphy CT - Search Results

1

Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria.

Mor DE, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, Miller GW, Murphy CT. Mor DE, et al. Among authors: murphy ct. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26438-26447. doi: 10.1073/pnas.2009838117. Epub 2020 Oct 6. Proc Natl Acad Sci U S A. 2020. PMID: 33024014 Free PMC article.

2

The role of insulin/IGF-like signaling in C. elegans longevity and aging.

Kaletsky R, Murphy CT. Kaletsky R, et al. Among authors: murphy ct. Dis Model Mech. 2010 Jul-Aug;3(7-8):415-9. doi: 10.1242/dmm.001040. Epub 2010 Mar 30. Dis Model Mech. 2010. PMID: 20354111 Free article. Review.

3

C. elegans positive butanone learning, short-term, and long-term associative memory assays.

Kauffman A, Parsons L, Stein G, Wills A, Kaletsky R, Murphy C. Kauffman A, et al. J Vis Exp. 2011 Mar 11;(49):2490. doi: 10.3791/2490. J Vis Exp. 2011. PMID: 21445035 Free PMC article.

4

PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity.

Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker HJ. Tepper RG, et al. Among authors: murphy ct. Cell. 2013 Aug 1;154(3):676-690. doi: 10.1016/j.cell.2013.07.006. Cell. 2013. PMID: 23911329 Free PMC article.

5

An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.

Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q. Fernandes de Abreu DA, et al. Among authors: murphy ct. PLoS Genet. 2014 Mar 27;10(3):e1004225. doi: 10.1371/journal.pgen.1004225. eCollection 2014 Mar. PLoS Genet. 2014. PMID: 24675767 Free PMC article.

6

Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs.

Lakhina V, Arey RN, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy CT. Lakhina V, et al. Among authors: murphy ct. Neuron. 2015 Jan 21;85(2):330-45. doi: 10.1016/j.neuron.2014.12.029. Neuron. 2015. PMID: 25611510 Free PMC article.

7

The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators.

Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, Murphy CT. Kaletsky R, et al. Among authors: murphy ct. Nature. 2016 Jan 7;529(7584):92-6. doi: 10.1038/nature16483. Epub 2015 Dec 14. Nature. 2016. PMID: 26675724 Free PMC article.

8

Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis.

Wang J, Kaletsky R, Silva M, Williams A, Haas LA, Androwski RJ, Landis JN, Patrick C, Rashid A, Santiago-Martinez D, Gravato-Nobre M, Hodgkin J, Hall DH, Murphy CT, Barr MM. Wang J, et al. Among authors: murphy ct. Curr Biol. 2015 Dec 21;25(24):3232-8. doi: 10.1016/j.cub.2015.10.057. Epub 2015 Dec 10. Curr Biol. 2015. PMID: 26687621 Free PMC article.

9

RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans.

Son HG, Seo M, Ham S, Hwang W, Lee D, An SW, Artan M, Seo K, Kaletsky R, Arey RN, Ryu Y, Ha CM, Kim YK, Murphy CT, Roh TY, Nam HG, Lee SV. Son HG, et al. Among authors: murphy ct. Nat Commun. 2017 Mar 9;8:14749. doi: 10.1038/ncomms14749. Nat Commun. 2017. PMID: 28276441 Free PMC article.

10

Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity.

Templeman NM, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy CT. Templeman NM, et al. Among authors: murphy ct. Curr Biol. 2018 Mar 5;28(5):753-760.e4. doi: 10.1016/j.cub.2018.01.052. Epub 2018 Feb 22. Curr Biol. 2018. PMID: 29478855 Free PMC article.

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